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Table 2 Odds ratio and 95% CI for MetS according to tertiles of serum sTWEAK concentrations

From: Reduced circulating sTWEAK levels are associated with metabolic syndrome in elderly individuals at high cardiovascular risk

  

Tertiles of sTWEAK concentrations

 
 

Continuous‡

1st tertile

2nd tertile

3rd tertile

P value for trend*

  

<453.1 ng/mL

453.1 to 706.4 < ng/mL

≥706.4 ng/mL

 

No. of MetS/No. of non-MetS

234/218

89/61

75/76

70/81

 

Crude model

1.39 (1.06 - 1.82)

1.69 (1.06 - 2.66)

1.14 (0.73 - 1.79)

1.00 [Ref.]

0.024

Model 1

1.40 (1.07 - 1.84)

1.71 (1.07 - 2.72)

1.15 (0.72 - 1.82)

1.00 [Ref.]

0.022

Model 2

1.49 (1.13 - 1.98)

1.85 (1.15 - 3.00)

1.21 (0.75 - 1.94)

1.00 [Ref.]

0.011

  1. Results expressed as odds ratios (95% CI) for MetS from logistic regression analysis. Abbreviations: MetS Metabolic Syndrome, sTWEAK soluble TNF-like weak inducer of apoptosis.
  2. Crude model: unadjusted; Model 1: Adjusted for gender and age; Model 2: Additionally adjusted for family history of diabetes and premature CHD (yes/no), educational level (primary education vs secondary/higher education), alcohol intake (g alcohol/d), smoking (current/not-current), physical activity (sedentary vs active) and eGFR. ‡Per unit decrease in log sTWEAK. *Linear trend tests were calculated using the median serum sTWEAK concentrations of each category and using them as a new continuous variable in the models.
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Cardiovascular Diabetology

ISSN: 1475-2840