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Table 2 Effects of 8-month liraglutide therapy (n = 64)

From: Liraglutide decreases carotid intima-media thickness in patients with type 2 diabetes: 8-month prospective pilot study

 

Baseline

After 4 months

After 8 months

p=

    

(for trend)

Weight (kg)

81 ± 17

78 ± 16*

78 ± 16*§

0.44

BMI (kg/m2)

30 ± 5

29 ± 5*

29 ± 5*§

0.28

Waist circumference (cm)

105 ± 14

102 ± 13*

102 ± 13*

0.36

Fasting glicemia (mmol/L)

8.9 ± 3.8

7.1 ± 1.6*

6.8 ± 1.9*

<0.0001

HbA1c (%)

8.4 ± 0.8

6.7 ± 0.9*

6.5 ± 0.8*

<0.0001

Total cholesterol (mmol/L)

4.4 ± 0.9

4.0 ± 0.7*

3.9 ± 0.7*

0.0020

Triglycerides (mmol/L)

1.8 ± 0.7

1.6 ± 0.7*

1.6 ± 0.7*

0.26

HDL-cholesterol (mmol/L)

1.07 ± 0.3

1.09 ± 0.3

1.16 ± 0.3*§

0.19

LDL-cholesterol (mmol/L)

2.5 ± 0.9

2.2 ± 0.6*

2.0 ± 0.7*

0.0011

Carotid IMT (mm)

1.19 ± 0.47

1.04 ± 0.35*

0.94 ± 0.21*§

0.0010

  1. *p < 0.01 vs baseline; §p < 0.01 vs. 4 months.