Parameter | SHAM | STZ |
---|---|---|
Body mass (g) | 538 ± 15 | 375 ± 13* |
Tibial length (mm) | 45.4 ± 0.6 | 42.2 ± 0.6* |
Lung mass (g) | 2.05 ± 0.09 | 1.89 ± 0.06 |
Lung mass/body mass (%) | 0.38 ± 0.02 | 0.52 ± 0.03* |
Heart mass (g) | 1.49 ± 0.05 | 1.16 ± 0.04* |
Heart mass/body mass (%) | 0.28 ± 0.01 | 0.31 ± 0.01* |
RV wall thickness (mm) | 1.33 ± 0.04 | 1.16 ± 0.06* |
LV wall thickness (mm) | 3.80 ± 0.09 | 3.74 ± 0.09 |
Septal wall thickness (mm) | 3.18 ± 0.07 | 3.14 ± 0.11 |
RV thickness/heart mass (mm g-1) | 0.91 ± 0.03 | 1.02 ± 0.06 |
LV thickness/heart mass (mm g-1) | 2.60 ± 0.10 | 3.26 ± 0.12* |
Septal thickness/heart mass (mm g-1) | 2.16 ± 0.07 | 2.74 ± 0.13* |
Blood glucose (mM) | 6.8 ± 0.1 | 29.6 ± 0.5* |
Systolic blood pressure (mmHg) | 129 ± 2.8 | 125 ± 2.9 |
Diastolic blood pressure (mmHg) | 84 ± 2.2 | 82 ± 2.2 |
Mean arterial blood pressure (mmHg) | 103 ± 2.3 | 102 ± 2.6 |
Heart rate in vivo (beats min-1) | 346 ± 16 | 302 ± 5* |
Heart rate in vitro (beats min-1) | 175 ± 7 | 156 ± 5* |