Figure 2
From: Kir6.2-containing ATP-sensitive K+ channel is required for cardioprotection of resveratrol in mice
Kir6.2 knockout abolished the protection of resveratrol against ischemia/reperfusion injury in mice. (A) Representative photograms of myocardial slices stained by Evans-blue/TTC. (B) Myocardial area at risk expressed as percentage of total area. (C) Myocardial infarct size expressed as percentage of AAR (n = 8/group). *P < 0.01 vs. corresponding I/R group; #P < 0.05 vs. WT I/R group. (D-E) Cardiac injury determined by serum CK (D) and LDH activity (E) (n = 8/group). Data are represented as means ± SEM. *P < 0.01 vs. corresponding sham group; #P < 0.01 vs. corresponding I/R group.