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Figure 2 | Cardiovascular Diabetology

Figure 2

From: Azilsartan, an angiotensin II type 1 receptor blocker, restores endothelial function by reducing vascular inflammation and by increasing the phosphorylation ratio Ser1177/Thr497 of endothelial nitric oxide synthase in diabetic mice

Figure 2

Vascular reactivity in aorta ring. Vascular reactivity to phenylephrine, acetylcholine, or sodium nitroprusside was determined using aortic rings isolated from male KKAy mice fed standard moderate fat (MF) diet (KKAy-Vehicle, ○) and MF mixed with 0.005% candesartan cilexetil (KKAy-Candesartan groups, □) or 0.005% azilsartan (KKAy-Azilsartan, ●) for 3 weeks since 8–10 weeks of age. Data represent the mean ± SEM. *p < 0.05, KKAy-vehicle versus KKAy-Azilsartan.

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Cardiovascular Diabetology

ISSN: 1475-2840