Implications of C1q/TNF-related protein-3 (CTRP-3) and progranulin in patients with acute coronary syndrome and stable angina pectoris

Table 3 Clinical and laboratory variables according to CTRP-3 level tertiles

	First tertile	Second tertile	Third tertile	P
CTRP-3 (ng/ml)	267.7 (239.6, 291.5)^a	367.8 (347.0, 401.0)^b	553.8 (477.9, 634.9)^c	<0.001
Age (years)	59 (54, 67)^a	58 (55, 68)^a	61 (58, 69)^b	0.019
Weight (kg)	67.8 ± 9.6^a	66.3 ± 11.7^a	63.2 ± 10.7^b	0.004
BMI (kg/m²)	24.4 ± 2.6	24.6 ± 3.0	24.0 ± 3.0	0.350
Waist circumference (cm)	85.9 ± 7.7^a	85.2 ± 8.2^a	82.5 ± 9.1^b	0.011
SBP (mmHg)	119 (112, 128)	123 (109.5, 134)	120.5 (109.5, 132)	0.570
DBP (mmHg)	75.4 ± 12.0	78.2 ± 12.2	75.4 ± 11.1	0.110
Total cholesterol (mmol/l)	4.7 ± 1.1	4.6 ± 1.0	4.7 ± 1.0	0.616
LDL-cholesterol (mmol/l)	3.2 ± 0.9	2.9 ± 0.9	3.1 ± 0.8	0.111
Triglyceride (mmol/l)	1.3 (0.9, 2.0)	1.3 (0.9, 2.0)	1.2 (0.9, 1.6)	0.132
HDL-cholesterol (mmol/l)	1.2 (1.0, 1.5)^a	1.2 (1.1, 1.4)^a	1.3 (1.2, 1.6)^b	0.001
Glucose (mmol/l)	5.7 (5.3, 6.4)^a,b	5.8 (5.3, 6.5)^a	5.5 (5.1, 6.0)^b	0.029
Creatinine (mg/dl)	0.8 (0.7, 0.9)	0.8 (0.6, 0.9)	0.8 (0.7, 0.9)	0.080
eGFR (mL/min/1.73 m²)	96.2 (84.1, 110.1)	97.9 (84.8, 110.7)	91.5 (82.0, 107.4)	0.127
hsCRP (mg/dl)	0.6 (0.2, 1.4)	0.7 (0.1, 1.4)	0.5 (0.1, 0.9)	0.157
Progranulin (ng/ml)	165.0 (135.9, 191.1)	169.4 (144.0, 213.2)	171.4 (148.8, 210.6)	0.116
Adiponectin (μg/ml)	6.4 (4.8, 8.5)^a	6.5 (5.2, 8.6)^a	8.6 (6.5, 11.7)^b	<0.001

Data are expressed as mean ± standard deviation or median (inter-quartile range).
SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL, low-density lipoprotein; HDL, high-density lipoprotein; eGFR, estimated glomerular filtration rate; hsCRP, high-sensitivity C-reactive protein; CTRP-3, C1q/TNF-related Protein-3.

ISSN: 1475-2840