|
Clinical parameters
|
Control (NGT)
|
T2DM
|
CAD
|
T2DM_CAD
|
|---|
|
n = 61
|
n = 60
|
n = 23
|
n = 21
|
|---|
|
Age (Years)
|
39.6 ± 13.7
|
56.4 ± 13.9a***
|
38.7 ± 15.8
|
60.9 ± 10.7c***
|
|
Body mass index (kg/m2)
|
23.19 ± 4.8
|
25.5 ± 5.2
|
21.1 ± 4.3
|
23.2 ± 4
|
|
Systolic BP (mm Hg)
|
114 ± 9.5
|
125 ± 2.2a**
|
122.5 ± 20.6
|
142.4 ± 19.9b**c**
|
|
Diastolic BP (mm Hg)
|
74.98 ± 8.5
|
77.2 ± 9.0
|
71.8 ± 10.03
|
87.3 ± 11.04b*
|
|
Fasting plasma glucose (mg/dL)
|
84.9 ± 9.1
|
158.9 ± 67.5a***
|
85.8 ± 12.5
|
136.2 ± 41.4c***
|
|
Glycated haemoglobin (%)
|
5.3 ± 0.37
|
8.5 ± 1.9a***
|
5.4 ± 0.5
|
7.6 ± 0.8c**
|
|
Total serum cholesterol (mg/dL)
|
174.5 ± 34.08
|
173.3 ± 46.02
|
188.2 ± 81.2
|
182.3 ± 37.1
|
|
Serum triglycerides (mg/dL)
|
108.2 ± 51.1
|
168.4 ± 100.4a***
|
105.1 ± 54.6
|
140.1 ± 77.4
|
|
HDL-cholesterol (mg/dL)
|
43 ± 7.9
|
40 ± 9.1
|
47.7 ± 12.6
|
41.9 ± 11.9
|
|
LDL-cholesterol (mg/dL)
|
107.7 ± 28.7
|
98.5 ± 37.9
|
119.5 ± 73.4
|
112.4 ± 33.3
|
|
VLDL-cholesterol (mg/dL)
|
20.2 ± 9.4
|
49.6 ± 51.5a***
|
20.9 ± 10.8
|
23.5 ± 11.4
|
|
Urea
|
20.5 ± 5.2
|
23.5 ± 8.7
|
20.8 ± 5.7
|
22.3 ± 4.1
|
|
Creatinine
|
0.85 ± 0.16
|
4.6 ± 11.7
|
0.8 ± 0.16
|
0.8 ± 0.24
|
|
Microalbuminuria (mg/dL)
|
16.4 ± 48.4
|
22.1 ± 33.9
|
15.1 ± 20.2
|
15 ± 16.4
|
- For all the parameters mean ± SD is reported. aComparison between Control and T2DM, bComparison between T2DM and T2DM-CAD, cComparison between CAD and T2DM-CAD. *P < 0.05, **P < 0.01, ***P < 0.0001.
