Increased Th1 and suppressed Th2 serum cytokine levels in subjects with diabetic coronary artery disease

Table 1 Clinical and biochemical characteristics of the study subjects

Clinical parameters	Control (NGT)	T2DM	CAD	T2DM_CAD
Clinical parameters	n = 61	n = 60	n = 23	n = 21
Age (Years)	39.6 ± 13.7	56.4 ± 13.9^a***	38.7 ± 15.8	60.9 ± 10.7^c***
Body mass index (kg/m²)	23.19 ± 4.8	25.5 ± 5.2	21.1 ± 4.3	23.2 ± 4
Systolic BP (mm Hg)	114 ± 9.5	125 ± 2.2^a**	122.5 ± 20.6	142.4 ± 19.9^bc
Diastolic BP (mm Hg)	74.98 ± 8.5	77.2 ± 9.0	71.8 ± 10.03	87.3 ± 11.04^b*
Fasting plasma glucose (mg/dL)	84.9 ± 9.1	158.9 ± 67.5^a***	85.8 ± 12.5	136.2 ± 41.4^c***
Glycated haemoglobin (%)	5.3 ± 0.37	8.5 ± 1.9^a***	5.4 ± 0.5	7.6 ± 0.8^c**
Total serum cholesterol (mg/dL)	174.5 ± 34.08	173.3 ± 46.02	188.2 ± 81.2	182.3 ± 37.1
Serum triglycerides (mg/dL)	108.2 ± 51.1	168.4 ± 100.4^a***	105.1 ± 54.6	140.1 ± 77.4
HDL-cholesterol (mg/dL)	43 ± 7.9	40 ± 9.1	47.7 ± 12.6	41.9 ± 11.9
LDL-cholesterol (mg/dL)	107.7 ± 28.7	98.5 ± 37.9	119.5 ± 73.4	112.4 ± 33.3
VLDL-cholesterol (mg/dL)	20.2 ± 9.4	49.6 ± 51.5^a***	20.9 ± 10.8	23.5 ± 11.4
Urea	20.5 ± 5.2	23.5 ± 8.7	20.8 ± 5.7	22.3 ± 4.1
Creatinine	0.85 ± 0.16	4.6 ± 11.7	0.8 ± 0.16	0.8 ± 0.24
Microalbuminuria (mg/dL)	16.4 ± 48.4	22.1 ± 33.9	15.1 ± 20.2	15 ± 16.4

For all the parameters mean ± SD is reported. ^aComparison between Control and T2DM, ^bComparison between T2DM and T2DM-CAD, ^cComparison between CAD and T2DM-CAD. *P < 0.05, **P < 0.01, ***P < 0.0001.

ISSN: 1475-2840