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Table 1 Effect of CAPA on plasma glucose levels in normal and diabetic rats

From: Caffeic acid phenethyl amide improves glucose homeostasis and attenuates the progression of vascular dysfunction in Streptozotocin-induced diabetic rats

CAPA (mg/kg)

Normal rats

Type 1 diabetic rats

Plasma glucose

% decrease in plasma glucose

n

Plasma glucose

% decrease in plasma glucose

n

 

Pre-treatment (mg/dL)

Post-treatment (mg/dL)

  

Pre-treatment (mg/dL)

Post-treatment (mg/dL)

  

Vehicle

138.5 ± 5.9

129.3 ± 2.2

5.8 ± 5.7

8

446.6 ± 11.6

444.1 ± 11.6

0.6 ± 0.1

8

0.1

124.3 ± 4.6

83.1 ± 3.7 *

32.9 ± 2.3 *

7

469.8 ± 37.2

409.8 ± 37.9

11.8 ± 5.5 *

4

0.5

120.5 ± 5.3

81.0 ± 5.7 *

32.8 ± 3.4 *

6

461.7 ± 21.3

394.0 ± 13.5 *

13.8 ± 4.3 *

7

1

126.2 ± 2.0

89.0 ± 3.2 *

29.5 ± 1.7 *

6

447.4 ± 25.5

393.7 ± 20.6 *

11.6 ± 1.7 *

11

  1. Plasma glucose was measured at 90 min after oral administration of vehicle or CAPA in overnight fasted rats. Rats treated with vehicle were used as controls. Data (mean ± SEM) were obtained from 4–11 animals. *P < 0.05 compared with the vehicle control group and examined by the paired t-test.
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Cardiovascular Diabetology

ISSN: 1475-2840