Comparative effect of clopidogrel and aspirin versus aspirin alone on laboratory parameters: a retrospective, observational, cohort study

Table 3 Mean changes in laboratory test values during exposure period from baseline

Laboratory test	Clopidogrel plus aspirin (n = 159)	Aspirin alone (n = 834)	p
	mean (95% CI)	mean (95% CI)
Δ WBC (10³/μL)
Unadjusted	−1.65 (−2.099, -1.202)	−0.455 (−0.651, -0.259)	<0.0001*
Propensity adjustment	−1.509 (−1.999, -1.018)	−0.312 (−0.803, 0.179)	0.0008*
Multivariate model	−1.832 (−2.317, -1.346)	−0.435 (−0.634, 0.237)	<0.0001*

Δ indicates mean change in laboratory test value during exposure period from baseline. Data that showed a significant difference are presented. Abbreviations: WBC white blood cell count, CI confidence interval. *: p < 0.05 (aspirin plus clopidogrel vs aspirin alone).

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