Table 1 Characteristics of participants
| Â | Control (n = 10) | Alogliptin (n = 10) | p value |
|---|---|---|---|
Age (years) | 35 ± 10 | - | - |
Male (%) | 8 (80) | - | - |
Current Smoker (%) | 3(30) | - | - |
HbA1c (%) | 4.6 ± 0.3 | - | - |
BMI (kg/m2) | 23.9 ± 4.1 | 23.9 ± 3.4 | 0.86 |
Systolic blood pressure (mmHg) | 122 ± 3 | 121 ± 3 | 0.35 |
Diastolic blood pressure (mmHg) | 71 ± 2 | 71 ± 2 | 0.99 |
Heart rate (beats/min) | 62 ± 3 | 61 ± 2 | 0.20 |
Total-C (mg/dl) | 185.3 ± 10.6 | 180.7 ± 9.9 | 0.58 |
LDL-C (mg/dl) | 103.2 ± 8.9 | 102.2 ± 9.3 | 0.72 |
HDL-C (mg/dl) | 66.3 ± 3.1 | 64.2 ± 3.4 | 0.29 |
TG (mg/dl) | 73.7 ± 10.2 | 63.4 ± 7.9 | 0.08 |
RLP-C (mg/dl) | 8.4 ± 1.2 | 6.7 ± 0.8 | 0.28 |
ApoB-48 (μg/ml) | 2.5 ± 0.3 | 2.2 ± 0.2 | 0.19 |
Glucose (mg/dl) | 93.0 ± 2.0 | 94.3 ± 2.1 | 0.54 |
Glucagon (pg/ml) | 63.5 ± 5.4 | 59.4 ± 2.8 | 0.44 |
Insulin (μIU/ml) | 4.8 ± 0.8 | 4.9 ± 1.3 | 0.38 |
HOMA-IR | 1.1 ± 0.2 | 1.1 ± 0.3 | 0.51 |
GLP-1 (pmol/l) | 3.2 ± 0.2 | 5.2 ± 0.7 | 0.03 |
Adiponectin (μg/ml) | 9.6 ± 0.8 | 9.7 ± 0.7 | 0.31 |
Soluble VCAM-1 (ng/ml) | 629 ± 72 | 606 ± 50 | 0.76 |