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Table 3 Association between categorical measures of kidney disease and all-cause mortality and cardiovascular disease (CVD) mortality

From: Glomerular filtration rate and albuminuria predict mortality independently from coronary artery calcified plaque in the Diabetes Heart Study

   

All-cause mortality

CVD-mortality

 

Quartiles

Quartlie ranges

HR (95% CI)

p-value

HR (95% CI)

p-value

Serum albumin†

Q1-Q3

3.2–4.4

1.54 (1.14–2.08)

0.005

1.35 (0.84–2.17)

0.21

Q4

4.4–5.3

Serum creatinine*

Q1-Q3

0.4–1.2

1.36 (0.99–1.87)

0.06

2.02 (1.24–3.29)

0.005

Q4

1.2–1.75

UACR*

Q1-Q3

0.5–37.9

1.81 (1.38–2.39)

1.99×10-5

2.38 (1.61–3.53)

1.50×10-5

Q4

37.9–4165.0

eGFR†

Q1-Q3

20.0–75.0

1.58 (1.16–2.16)

0.004

1.94 (1.23–3.05)

0.004

Q4

75.0–179.9

  1. UACR=urine albumin:creatinine ratio; eGFR=estimated glomerular filtration rate.
  2. Associations based on proportional hazards regression models adjusted for age, sex, type 2 diabetes affection status, body mass index, current smoking, hypertension, dyslipidemia, ACE/ARB medication use, prior CVD and coronary artery calcified plaque.
  3. *For serum creatinine and UACR, quartiles were established based on increasing values across the distribution such that quartile 4 (Q4) captures the highest risk individuals. †For serum albumin and eGFR, quartiles were established based on decreasing values across the distribution such that Q4 again captures the highest risk individuals.
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Cardiovascular Diabetology

ISSN: 1475-2840