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Table 3 Association between categorical measures of kidney disease and all-cause mortality and cardiovascular disease (CVD) mortality

From: Glomerular filtration rate and albuminuria predict mortality independently from coronary artery calcified plaque in the Diabetes Heart Study

    All-cause mortality CVD-mortality
  Quartiles Quartlie ranges HR (95% CI) p-value HR (95% CI) p-value
Serum albumin† Q1-Q3 3.2–4.4 1.54 (1.14–2.08) 0.005 1.35 (0.84–2.17) 0.21
Q4 4.4–5.3
Serum creatinine* Q1-Q3 0.4–1.2 1.36 (0.99–1.87) 0.06 2.02 (1.24–3.29) 0.005
Q4 1.2–1.75
UACR* Q1-Q3 0.5–37.9 1.81 (1.38–2.39) 1.99×10-5 2.38 (1.61–3.53) 1.50×10-5
Q4 37.9–4165.0
eGFR† Q1-Q3 20.0–75.0 1.58 (1.16–2.16) 0.004 1.94 (1.23–3.05) 0.004
Q4 75.0–179.9
  1. UACR=urine albumin:creatinine ratio; eGFR=estimated glomerular filtration rate.
  2. Associations based on proportional hazards regression models adjusted for age, sex, type 2 diabetes affection status, body mass index, current smoking, hypertension, dyslipidemia, ACE/ARB medication use, prior CVD and coronary artery calcified plaque.
  3. *For serum creatinine and UACR, quartiles were established based on increasing values across the distribution such that quartile 4 (Q4) captures the highest risk individuals. †For serum albumin and eGFR, quartiles were established based on decreasing values across the distribution such that Q4 again captures the highest risk individuals.