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Table 2 Data from the female diabetic population and age-matched controls: menopause influence

From: Diabetes abrogates sex differences and aggravates cardiometabolic risk in postmenopausal women

  Female control group Female diabetic group Diabetic vs control (P)
Parameters Pre-M (n = 16) Post-M (n = 19) P Pre-M (n = 8) Post-M (n = 45) P Pre-menopausal Post- menopausal
Age (years) 45.63 ± 1.12 62.37 ± 1.35 0.000 43.88 ± 1.29 63.44 ± 1.20 0.000 0.349 0.345
BMI (Kg/m2) 26.93 ± 1.21 27.21 ± 0.85 0.472 29.43 ± 2.44 30.24 ± 0.67 0.578 0.221 0.013
WC (cm) 91.38 ± 2.86 93.06 ± 2.75 0.575 100.57 ± 4.93 104.66 ± 2.27 0.081 0.103 0.000
SBP (mmHg) 132.69 ± 5.62 153.56 ± 4.61 0.004 120.38 ± 7.22 140.58 ± 3.91 0.048 0.187 0.113
DBP (mmHg) 84.25 ± 3.20 90.89 ± 2.52 0.175 72.25 ± 3.14 72.82 ± 2.02 0.519 0.027 0.000
Glycemia (mmol/L) 4.92 ± 0.10 5.31 ± 0.14 0.038 10.80 ± 1.65 10.67 ± 0.64 0.832 0.000 0.000
HbA1c (%) 9.03 ± 1.08 9.23 ± 0.30 0.477
Total-c (mmol/L) 5.08 ± 0.16 5.48 ± 0.21 0.364 4.68 ± 0.44 4.93 ± 0.16 0.725 0.313 0.090
TGs (mmol/L) 1.02 ± 0.08 1.13 ± 0.10 0.455 1.51 ± 0.31 2.08 ± 0.17 0.467 0.066 0.003
LDL-c (mmol/L) 3.21 ± 0.17 3.47 ± 0.19 0.514 2.71 ± 0.35 2.69 ± 0.15 0.997 0.164 0.007
Ox-LDL (U/L) 29.13 ± 1.76 36.46 ± 2.98 0.044 34.83 ± .58 31.89 ± 1.61 0.993 0.897 0.339
Non-HDL-c (mmol/L) 3.68 ± 0.17 4.01 ± 0.20 0.390 3.36 ± 0.45 3.60 ± 0.17 0.781 0.236 0.243
PON1 activity 415.66 ± 26.78 477.17± 32.14 0.420 443.94 ± 31.40 498.39 ± 35.22 0.089 0.527 0.916
  1. Results are presented as media ± SEM. Independent samples T-test and Mann–Whitney test for normalized and non-normalized samples, respectively. P adjusted for age and BMI (ANCOVA) when adequate (when p<0.05): for age when comparing pre vs postmenopausal women (both in control and diabetic subjects); for BMI when comparing postmenopausal diabetic women vs postmenopausal control subjects. BMI, body mass index; HbA1c, glycated hemoglobin; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL-c, low-density lipoprotein cholesterol; Ox-LDL, oxidized low-density lipoprotein; TGs, triglycerides; Total-c, total cholesterol; WC, waist circumference.