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Figure 2 | Cardiovascular Diabetology

Figure 2

From: Antidiabetic treatment restores adiponectin serum levels and APPL1 expression, but does not improve adiponectin-induced vasodilation and endothelial dysfunction in Zucker diabetic fatty rats

Figure 2

Dose-dependent relaxation of resistance arteries to cumulative doses of adiponectin after precontraction with norepinephrine. Adiponectin-induced vasodilation is restricted in untreated ZDF animals and remains unchanged by insulin or metformin treatment. Two-way ANOVA for repeated measurements: * p = 0.002 vs. ZDF and ZDF+I, p = 0.001 vs ZDF+M; # p = 0.002 vs ZDF.

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Cardiovascular Diabetology

ISSN: 1475-2840