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Table 1 Estimated parameters and coefficients of the two models

From: Blood glucose may be an alternative to cholesterol in CVD risk prediction charts

  Model with glucose Glucose vs. cholesterol Model with cholesterol
  Estimate (95% CI) P-value Estimate (P-value) Estimate (95% CI) P-value
α men −47.7 (−50.7; -44.4) <0.001   −47.5 (−50.7; -44.4) <0.001
p men 9.9 (9.2; 10.6) <0.001   9.9 (9.2; 10.6) <0.001
α women −58.8 (−62.7; -54.9) <0.001   −58.5 (−62.4; -54.6) <0.001
p women 12.4 (11.5; 13.2) <0.001   12.5 (11.7; 13.1) <0.001
Current smoking 0.37 (0.20; 0.54) <0.001   0.34 (0.17; 0.51) <0.001
Systolic blood pressure (mmHg) 0.01 (0.01; 0.02) <0.001   0.01 (0.01; 0.02) <0.001
Glucose (mmol/l) 0.10 (0.06; 0.14) <0.001    
Cholesterol (mmol/l)     0.10 (0.00; 0.20) 0.046
Model comparison      
Brier score (mean, cross-validated) 2216 x 10-5   (0.287) 2232 x 10-5  
AUC (cross-validated) 0.9181    0.9169  
IDI (glucose vs. cholesterol)    0.009 (0.026)   
Model comparison, external validation*      
Brier score (mean) 7662 x 10-5   (0.245) 7744 x 10-5  
AUC 0.8766    0.8737  
IDI (glucose vs. cholesterol)    0.029 (<0.001)   
  1. *with data from the third National Health and Nutrition Examination Survey (NHANES III).
  2. AUC area under the receiver-operating characteristic curve; IDI integrated discrimination improvement.