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Table 2 Conduction velocity, diastolic and developed force

From: Myocardial impulse propagation is impaired in right ventricular tissue of Zucker Diabetic Fatty (ZDF) rats

 

ZDF

ZDL

 

Control (n=8)

AAP10 (n=8)

Control (n=10)

AAP10 (n=11)

Conduction velocity (cm/s)

Baseline

55.9 ± 2.3 #

56.2 ± 3.4 #

66.0 ± 2.9

66.7 ± 1.7

Treatment

57.8 ± 3.2 #

57.9 ± 3.5 #

67.9 ± 2.9

67.0 ± 2.0

Diastolic force (mg/mm 2 )

Baseline

317 ± 53

380 ± 81

216 ± 44

263 ± 44

Treatment

333 ± 53

386 ± 76

202 ± 38

258 ± 40

Developed force (mg/mm 2 )

Baseline

331 ± 29 *#

206 ± 29

223 ± 25

234 ± 23

Treatment

330 ± 36 *#

239 ± 33

252 ± 27

271 ± 26

  1. Conduction velocity, diastolic and developed force in control (vehicle treated) and AAP10 treated strips from ZDF and ZDL rats. Data are shown as mean ± SEM during the last 10 min of each period (* P<0.05 for control versus AAP 10; # P<0.05 for ZDF versus ZDL, analyzed by factorial ANOVA followed by Fisher’s LSD post-hoc test).