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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes

Figure 3

Eplerenone reduced apoptosis in HF-stimulated cardiomyocytes. (A) By flow cytometry, detection of apoptotic cardiomyocytes (sub G0/G1 phase) after HF (0.12 mM) and HF+eplerenone (10-6 M). (B) Caspase-3 activation. (C) Cell viability assayed by MTT in cardiomyocytes stimulated with HF and/or eplerenone. *p < 0.05 and **p < 0.01 vs. related control. †p < 0.05 and ††p < 0.01 vs. HF.

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Cardiovascular Diabetology

ISSN: 1475-2840