Plasma renin levels and prorenin receptor and AT
expression in cardiac myocytes. Plasma renin (A) and AT2(C) levels were determined by Western blot analysis and PRR (B) expression was measured by real-time RT-PCR, in control, diabetic (STZ + Veh), and diabetic mice treated with different RAS inhibitors, after 10 wks of diabetes (C). Representative Western blot images are shown. Values are expressed as the fold change compared to control ± SEM. *P < 0.05 vs. control.