Establishment of diabetic rat model. Columns indicate values of Ctrl, NAC, DCM and DCM + NAC in a (mean ± SD) manner respectively. (a) Fasting blood glucose concentration was examined after modeling. (b) Body weight was measured after modeling. (c) and (d) LVESP, LVSP, LV dp/dt max and LV dp/dt min in different groups are detected by invasive hemodynamic determination. (e) Plasma BNP concentration (pg/mL) was determined by Triage BNP Assay. a Values are significantly different from Ctrl; b values are significantly different from NAC; c values are significantly different from DCM. [(&)P < 0.05; (#)P < 0.01; (*)P < 0.001].