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Figure 6 | Cardiovascular Diabetology

Figure 6

From: Interferon regulatory factor-1 together with reactive oxygen species promotes the acceleration of cell cycle progression by up-regulating the cyclin E and CDK2 genes during high glucose-induced proliferation of vascular smooth muscle cells

Figure 6

Western blot analysis of cyclin E and CDK2 in transfected VSMCs following treatment with U0126. a: Western blot analysis of the expression of cyclin E and CDK2 protein levels in transfected VSMCs; b: quantitative assessment of cyclin E and CDK2 protein levels through integrated optical density analyses. High glucose/U0126 = cells incubated with high glucose and U0126 for 5 days; normal glucose/H2O2/U0126 = cells incubated with normal glucose, H2O2 and U0126 for 5 days. *P <0.05; **P <0.01 versus corresponding values in untransfected VSMCs.

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Cardiovascular Diabetology

ISSN: 1475-2840