Figure 2From: Interferon regulatory factor-1 together with reactive oxygen species promotes the acceleration of cell cycle progression by up-regulating the cyclin E and CDK2 genes during high glucose-induced proliferation of vascular smooth muscle cellsExamination of the expression of cyclins/CDK in transfected VSMCs under high glucose. a: Western blot analysis of cyclin D1, CDK4, cyclin E and CDK2 after 5Â days of incubation of the transfected VSMCs with high glucose; b: quantitative assessment of cyclin/CDK protein levels through integrated optical density analyses. *P <0.05; **P <0.01 versus corresponding values in untransfected VSMCs.Back to article page