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Table 2 Echocardiographic parameters in the population according to the absence or presence of diabetes

From: The activity of circulating dipeptidyl peptidase-4 is associated with subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus

Parameters

Non-diabetic subjects

Diabetic patients

p value

(n = 59)

(n = 83)

LV Morphology

   

LVEDVindex (mL/m2)

64.9 ± 14.8

63.9 ± 15.3

0.714

LVESVindex (mL/m2)

22.5 ± 7.8

23.1 ± 8.6

0.695

IVSTd (mm)

10 (8-11)

10 (9-12)

0.033

PWTd (mm)

10 (9-12)

11 (10-12)

0.448

RWT

0.40 ± 0.06

0.44 ± 0.08

0.026

Prevalence of LV concentric geometry (n, %)

21, 36

49, 59

0.008

LVM/BSA (g/m2)

94.3 (80.1-126)

105 (87.8-127)

0.228

Prevalence of LVH (n, %)

27, 46

37, 44

0.510

Observed/predicted LVM (%)

118 ± 31

133 ± 34.7

0.025

Prevalence of inappropriate LVM (n, %)

16, 27

43, 52

0.007

LA Morphology

   

LA long-axis (cm)

4.9 ± 0.7

5.2 ± 0.8

0.021

LA minor-axis (cm)

3.7 ± 0.7

3.8 ± 0.7

0.385

LA ap (cm)

3.6 ± 0.7

3.7 ± 0.8

0.448

LA volume index (mL/m2)

19.2 (14.6-25.1)

18.1 (14.9-27.6)

0.863

Prevalence of LA enlargement (n,%)

7, 12

19, 23

0.093

LV diastolic function

   

E (cm/s)

74.6 ± 15.2

78.1 ± 20.1

0.353

A (cm/s)

84.3 ± 18.9

88.4 ± 19.5

0.241

E/A ratio

0.91 ± 0.23

0.83 ± 0.16

0.042

IVRT (ms)

110 (90-121)

100 (90-120)

0.113

DT (ms)

220 (180-258)

220 (190-260)

0.811

e' (cm/s)

9.1 ± 2.5

8.3 ± 2.4

0.151

E/e'

8.5 (6.6-10.5)

9.3 (7.6-12)

0.046

a' (cm/s)

10.4 ± 2.8

11.4 ± 3

0.088

e'/a'

0.74 (0.58-1.2)

0.66 (0.54-0.78)

0.028

Prevalence of LV diastolic dysfunction (n, %)

3, 5.2

30, 36.6

<0.001

LV systolic function

   

LVSWi (g/cm-2)

85.2 ± 13.8

78.9 ± 15.6

0.017

LVEF (%)

65.1 ± 6.7

62.2 ± 6.2

0.010

FS (%)

35.9 ± 5.1

33.5 ± 4.8

0.007

MFS (%)

16.8 ± 3

15.8 ± 2.6

0.045

cESS (kdyne/cm2)

142 (117-176)

139 (118-175)

0.854

mESS (kdyne/cm2)

77.3 ± 18.5

73.1 ± 20.2

0.213

cESS-MFS (%)

99.9 ± 18

94.1 ± 14.8

0.042

mESS/LVESVi (107 dyne/cm3)

3.3 (2.4-4.8)

2.9 (2.1-2.9)

0.071

Prevalence of LV systolic dysfunction (n, %)

4, 6.8

17, 20.5

0.019

  1. LV means left ventricular; LVEDVi, LV end-diastolic volume index; LVESVi, LV end-systolic volume index; IVSTd, interventricular septum thickness in diastole; PWTd, posterior wall thickness in diastole; RWT, relative wall thickness; LVM, LV mass; BSA, body surface area; LVH, left ventricular hypertrophy; LA, left atrial; E, maximum early transmitral velocity in diastole; A, maximum late transmitral velocity in diastole; IVRT, isovolumic relaxation time; DT, deceleration time; e’, early mitral annulus velocity; a’, late mitral annulus velocity; LVSWi, LV stroke work index; LVEF, LV ejection fraction; FS, subendocardial fractional shortening; MFS, midwall fractional shortening; cESS, circumferential end-systolic stress; mESS, meridional end-systolic stress. Values are expressed as mean ± SD or median (interquartile range), and categorical variables as numbers and percentages.
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Cardiovascular Diabetology

ISSN: 1475-2840