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Table 3 Factors associated with the serum GGT level stratified by the ALDH2 genotype

From: Association between aldehyde dehydrogenase 2 polymorphisms and the incidence of diabetic retinopathy among Japanese subjects with type 2 diabetes mellitus

 

ALDH2*1/*1 genotype

ALDH2*2 allele carrier

 

β

SE

P value

β

SE

P value

Age

−0.37

0.48

0.45

−0.70

0.30

0.02

Diabetes duration

−0.75

0.72

0.30

−1.38

0.57

0.02

BMI

0.52

1.39

0.71

1.80

0.87

0.04

Systolic BP

−0.22

0.30

0.94

0.29

0.14

0.046

Diastolic BP

0.50

0.47

0.30

0.62

0.24

0.01

Triglycerides

0.22

0.03

< 0.01

0.07

0.03

0.02

AST

1.48

0.24

< 0.01

0.97

0.18

< 0.01

ALT

0.85

0.16

< 0.01

0.56

0.10

< 0.01

Hypertension

1.10

11.33

0.92

13.34

6.12

0.03

Ever smokers

13.23

11.46

0.25

16.48

6.09

< 0.01

Drinkers

26.07

11.68

0.03

8.79

6.80

0.20

HbA1c

4.23

2.64

0.11

1.15

1.52

0.45

  1. GGT, γ-glutamyltransferase; ALDH2, aldehyde dehydrogenase 2; SE, standard error; BMI, body mass index; BP, blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; HbA1c, hemoglobin A1c.