Table 1 Descriptive variables on the experimental day (at week 8)

Body-weight (g)

438 ± 7 (28)

247 ± 8 (28) ^a

269 ± 5 (26) ^{b, c}

<0.0001

Heart-weight (g)

1.60 ± 0.07 (24)

1.24 ± 0.06 (24) ^a

1.25 ± 0.05 (20) ^c

<0.0001

Tibial length (cm)

4.23 ± 0.04 (13)

3.86 ± 0.06 (16) ^a

3.87 ± 0.06 (20) ^c

<0.0001

Heart weight/Body-weight (x 10 ³ )

3.7 ± 0.1 (23)

5.3 ± 0.2 (21) ^a

5.0 ± 0.2 (20) ^c

<0.0001

Heart weight/ (Tibial length) ² (mg/cm ² )

94 ± 4 (13)

90 ± 5 (13)

84 ± 3 (20)

0.23

Blood glucose (mmol/L)

4.7 ± 0.1 (24)

30.8 ± 0.8 (30) ^a

32.2 ± 0.7 (26) ^c

<0.0001

Heart rate (min ^-1 )

390 ± 9 (11)

311 ± 6 (18) ^a

315 ± 12 (10) ^c

<0.0001

Corrected QT interval (ms)

177 ± 4 (11)

192 ± 4 (18) ^a

138 ± 14 (10) ^b

0.001