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Table 1 Descriptive variables on the experimental day (at week 8)

From: Protection of the heart by treatment with a divalent-copper-selective chelator reveals a novel mechanism underlying cardiomyopathy in diabetic rats

  Control Diabetic TETA-treated diabetic P
Body-weight (g) 438 ± 7 (28) 247 ± 8 (28) a 269 ± 5 (26) b, c <0.0001
Heart-weight (g) 1.60 ± 0.07 (24) 1.24 ± 0.06 (24) a 1.25 ± 0.05 (20) c <0.0001
Tibial length (cm) 4.23 ± 0.04 (13) 3.86 ± 0.06 (16) a 3.87 ± 0.06 (20) c <0.0001
Heart weight/Body-weight (x 10 3 ) 3.7 ± 0.1 (23) 5.3 ± 0.2 (21) a 5.0 ± 0.2 (20) c <0.0001
Heart weight/ (Tibial length) 2 (mg/cm 2 ) 94 ± 4 (13) 90 ± 5 (13) 84 ± 3 (20) 0.23
Blood glucose (mmol/L) 4.7 ± 0.1 (24) 30.8 ± 0.8 (30) a 32.2 ± 0.7 (26) c <0.0001
Heart rate (min -1 ) 390 ± 9 (11) 311 ± 6 (18) a 315 ± 12 (10) c <0.0001
Corrected QT interval (ms) 177 ± 4 (11) 192 ± 4 (18) a 138 ± 14 (10) b 0.001
  1. Data are means ± SEM. Numbers of animals were as shown in parentheses. P-values are by Kruskal-Wallis one-way ANOVA with Dunn’s multiple-comparisons test or one-way ANOVA with the Holm-Sidak method as appropriate; a, b, c, significant differences: a, Control vs Diabetic groups; b, Diabetic vs TETA-treated diabetic; c, Control vs TETA-treated Diabetic.