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Table 3 Genotype and allele frequencies of rs9770242 by CAD status

From: Association of circulating levels of nicotinamide phosphoribosyltransferase (NAMPT/Visfatin) and of a frequent polymorphism in the promoter of the NAMPT gene with coronary artery disease in diabetic and non-diabetic subjects

  N rs9770242 OR (95% CI) P
   MAF TT TG GG   
Brazilian cohort        
Without CAD 188 0.245 0.582 (n = 109) 0.351 (n = 66) 0.067 (n = 13) 1  
With CAD 406 0.201 0.639 (n = 259) 0.323 (n = 131) 0.038 (n = 16) 1.36 (1.01 – 1.86)a 0.05
1.46 (1.06 – 2.01)b 0.02
North-American cohort        
Without CAD 434 0.247 0.562 (n = 244) 0.383 (n = 166) 0.055 (n = 24) 1  
With CAD 424 0.245 0.543 (n = 230) 0.424 (n = 180) 0.033 (n = 14) 1.02 (0.76 – 1.22)c 0.73
  1. OR (odds ratio) in a codominant model for the T-allele determined in logistic regression analyses.(a)Adjusted for sex, age and glycemic status; (b)adjusted for sex, age, glycemic status, BMI, blood pressure, dyslipidemia and NAMPT levels; (c)adjusted for age and sex. MAF: minor allele frequency. Hardy-Weinberg equilibrium: Brazilian cohort, without CAD (p = 0.49), with CAD (p = 0.91); North-American cohort, without CAD (p = 0.54), with CAD (p = 0.003).