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Figure 1 | Cardiovascular Diabetology

Figure 1

From: Dual renin-angiotensin system inhibition for prevention of renal and cardiovascular events: do the latest trials challenge existing evidence?

Figure 1

Schematic representation of the RAS. ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; AT1, angiotensin II type 1 receptor; AT2, angiotensin II type 2 receptor; DRI, direct renin inhibitor; NO, nitric oxide; PRA, plasma renin activity; PRC, plasma renin concentration; RAS, renin-angiotensin system; SNS, sympathetic nervous system; tPA, tissue plasminogen activator. Adapted from Farsang 2011 [9].

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Cardiovascular Diabetology

ISSN: 1475-2840