Table 1 Characteristics of coronary artery disease patients
Parameter | All | Mild CAD | Moderate-severe CAD | P value |
|---|---|---|---|---|
(n =170) | (SSS ≤8, n = 88) | (SSS >8, n = 82) | ||
Age (yr) | 65.7 ± 13.6 | 64.0 ± 13.1 | 67.6 ± 13.9 | 0.09 |
Male gender (%) | 115 (68%) | 55 (63%) | 50 (73%) | 0.14 |
Body mass index (kg/m2) | 24.9 ± 3.7 | 24.9 ± 3.5 | 24.9 ± 4.1 | 0.99 |
Waist (cm) | 85 ± 11 | 86 ± 12 | 84 ± 11 | 0.41 |
Hypertension (%) | 73 (43%) | 36 (41%) | 37 (45%) | 0.58 |
Diabetes mellitus (%) | 36 (21%) | 14 (16%) | 22 (27%) | 0.08 |
Smoking (%) | 43 (25%) | 14 (16%) | 29 (35%) | 0.004 |
LVEF | 0.61 ± 0.16 | 0.68 ± 0.13 | 0.53 ± 0.16 | < 0.0001 |
Creatinine (mg/dL) | 1.13 ± 0.45 | 1.03 ± 0.34 | 1.22 ± 0.53 | 0.005 |
Fasting glucose (mg/dL) | 116 ± 45 | 110 ± 42 | 123 ± 47 | 0.07 |
Total cholesterol (mg/dL) | 186 ± 47 | 184 ± 38 | 189 ± 57 | 0.58 |
HDL-C (mg/dL) | 48 ± 16 | 51 ± 18 | 44 ± 12 | 0.006 |
LDL-C (mg/dL) | 108 ± 34 | 105 ± 26 | 111 ± 41 | 0.25 |
ALT (U/L) | 29 ± 19 | 27 ± 19 | 30 ± 20 | 0.18 |
hsCRP (ug/mL)* | 2.3 (1.1, 8.2) | 1.8 (0.6, 4.6) | 3.0 (1.7, 11.9) | 0.0005 |
NT-proBNP (ng/L)* | 107 (42, 797) | 63 (38, 127) | 797 (129, 2572) | < 0.0001 |
Adiponectin (mg/L)* | 7.6 (5.2, 12.3) | 7.4 (5.0, 10.0) | 7.7 (5.3, 15.7) | 0.13 |
A-FABP (ng/mL)* | 26.2 (17.2, 40.1) | 21.1 (16.2, 33.8) | 32.4 (19.7, 48.5) | 0.002 |
Medications | Â | Â | Â | Â |
 ACEi/ARBs  | 101 (59%) | 34 (39%) | 67 (82%) | < 0.0001 |
 Beta-blockers  | 57 (34%) | 23 (26%) | 34 (41%) | 0.03 |
 CCBs  | 39 (23%) | 24 (27%) | 15 (18%) | 0.16 |
 Diuretics  | 51 (30%) | 14 (16%) | 37 (45%) | < 0.0001 |
 Statins  | 36 (21%) | 12 (14%) | 24 (29%) | 0.01 |
 Metformin  | 12 (7%) | 5 (6%) | 7 (9%) | 0.47 |