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Table 4 Chronic hypoglycaemic effect of Cinnamomum tamala oil on STZ induced diabetic rats

From: GC-MS analysis and screening of antidiabetic, antioxidant and hypolipidemic potential of Cinnamomum tamala oil in streptozotocin induced diabetes mellitus in rats

Treatment Dose Mean blood glucose concentration (mg/dl) ± S.E.M
0thDay 7thDay 14thDay 21stDay 28th
Normal -- 80 ± 4.2 79 ± 3.2 82 ± 2.5 85.5 ± 4.1 78 ± 2.1
Control -- 380 ± 7.3 379 ± 7.6 384 ± 6.7 416 ± 7.2 410 ± 5.4
CTO 100 mg/kg p.o 304 ± 12.4 290 ± 8.6** 276 ± 7.8** 250 ± 9.9** 201 ± 10.2**
CTO 200 mg/kg p.o 312 ± 5.7 269 ± 6.3** 176 ± 5.5** 146 ± 4.5** 118 ± 5.5**
Cinnamaldehyde 20 mg/kg p.o 334 ± 3.4 287 ± 4.2** 188 ± 3.2** 159 ± 4.6** 124 ± 3.2**
Glibenclamide 0.6 mg/kg p.o 328 ± 3.1 265 ± 2.9** 172 ± 3.9** 142 ± 4.9** 117 ± 2.7**
  1. Values are presented as mean ± S.E.M.; n = 6 in each group. One way ANOVA followed by Dunnett’s test **p < 0.01 vs. diabetic control; CTO: Cinnamomum tamala oil.