GC-MS analysis and screening of antidiabetic, antioxidant and hypolipidemic potential of Cinnamomum tamala oil in streptozotocin induced diabetes mellitus in rats

Table 4 Chronic hypoglycaemic effect of Cinnamomum tamala oil on STZ induced diabetic rats

Treatment	Dose	Mean blood glucose concentration (mg/dl) ± S.E.M
Treatment	Dose	0^thDay	7^thDay	14^thDay	21^stDay	28^th
Normal	--	80 ± 4.2	79 ± 3.2	82 ± 2.5	85.5 ± 4.1	78 ± 2.1
Control	--	380 ± 7.3	379 ± 7.6	384 ± 6.7	416 ± 7.2	410 ± 5.4
CTO	100 mg/kg p.o	304 ± 12.4	290 ± 8.6**	276 ± 7.8**	250 ± 9.9**	201 ± 10.2**
CTO	200 mg/kg p.o	312 ± 5.7	269 ± 6.3**	176 ± 5.5**	146 ± 4.5**	118 ± 5.5**
Cinnamaldehyde	20 mg/kg p.o	334 ± 3.4	287 ± 4.2**	188 ± 3.2**	159 ± 4.6**	124 ± 3.2**
Glibenclamide	0.6 mg/kg p.o	328 ± 3.1	265 ± 2.9**	172 ± 3.9**	142 ± 4.9**	117 ± 2.7**

Values are presented as mean ± S.E.M.; n = 6 in each group. One way ANOVA followed by Dunnett’s test **p < 0.01 vs. diabetic control; CTO: Cinnamomum tamala oil.

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