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Table 3 Acute hypoglycaemic effect of Cinnamomum tamala oil on STZ induced diabetic rats

From: GC-MS analysis and screening of antidiabetic, antioxidant and hypolipidemic potential of Cinnamomum tamala oil in streptozotocin induced diabetes mellitus in rats

Treatment Dose Mean blood glucose concentration (mg/dl) ± S.E.M)
0 h 1/2 h 1 h 2 h 4 h
Normal -- 76 ± 4.2 80 ± 3.2 77 ± 2.5 82 ± 4.1 79 ± 5.3
Control -- 340.5 ± 10.2 342 ± 11.3 346 ± 7.6 341.0 ± 6.7 332.0 ± 7.2
CTO 100 mg/kg p.o 356 ± 6.7 334.1 ± 6.2 308 ± 3.6** 301 ± 3.0** 292 ± 3.3**
CTO 200 mg/kg p.o 347 ± 1.8 324 ± 0.7* 301 ± 2.3** 295 ± 1.5** 272 ± 6.5**
Cinnamaldehyde 20 mg/kg p.o 329 ± 3.2 302 ± 4.2** 299 ± 3.2** 270 ± 4.6** 262 ± 5.3**
Glibenclamide 0.6 mg/kg p.o 334 ± 3.1 320 ± 2.9** 296 ± 3.9** 279 ± 4.9** 260.0 ± 4.2**
  1. Values are presented as mean ± S.E.M.; n = 6 in each group. One way ANOVA followed by Dunnett’s test *p < 0.05; **p < 0.01 vs. diabetic control; CTO: Cinnamomum tamala oil.