GC-MS analysis and screening of antidiabetic, antioxidant and hypolipidemic potential of Cinnamomum tamala oil in streptozotocin induced diabetes mellitus in rats

Table 3 Acute hypoglycaemic effect of Cinnamomum tamala oil on STZ induced diabetic rats

Treatment	Dose	Mean blood glucose concentration (mg/dl) ± S.E.M)
Treatment	Dose	0 h	1/2 h	1 h	2 h	4 h
Normal	--	76 ± 4.2	80 ± 3.2	77 ± 2.5	82 ± 4.1	79 ± 5.3
Control	--	340.5 ± 10.2	342 ± 11.3	346 ± 7.6	341.0 ± 6.7	332.0 ± 7.2
CTO	100 mg/kg p.o	356 ± 6.7	334.1 ± 6.2	308 ± 3.6**	301 ± 3.0**	292 ± 3.3**
CTO	200 mg/kg p.o	347 ± 1.8	324 ± 0.7*	301 ± 2.3**	295 ± 1.5**	272 ± 6.5**
Cinnamaldehyde	20 mg/kg p.o	329 ± 3.2	302 ± 4.2**	299 ± 3.2**	270 ± 4.6**	262 ± 5.3**
Glibenclamide	0.6 mg/kg p.o	334 ± 3.1	320 ± 2.9**	296 ± 3.9**	279 ± 4.9**	260.0 ± 4.2**

Values are presented as mean ± S.E.M.; n = 6 in each group. One way ANOVA followed by Dunnett’s test *p < 0.05; **p < 0.01 vs. diabetic control; CTO: Cinnamomum tamala oil.

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