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Table 3 Changes in hemodynamic, arterial stiffness and metabolic parameters in control group during 12 months follow up

From: Relation between augmentation index and adiponectin during one-year metformin treatment for nonalcoholic steatohepatosis: effects beyond glucose lowering?

Variable

Placebo group

Baseline

4 month

p-value V1 vs V2

12 month

p-value V1 vs V3

Systolic BP (mm/Hg)

133.0 ± 19.5

139.8 ± 19.3

0.091

125.4 ± 25.5

0.477

Diastolic BP (mm/Hg)

73.3 ± 14.1

75.0 ± 9.4

0.589

73.5 ± 11.9

0.842

Aortic AP (mm/Hg)

15.6 ± 9.3

20.2 ± 18.6

0.271

17.2 ± 12

0.587

AI (%)

29.9 ± 11.0

29.0 ± 11.5

0.625

34.6 ± 12.1

0.089

Total Cholesterol (mg/dl)

190.0 ± 38.5

186.2 ± 32.6

0.616

175.8 ± 30.6

0.024

Triglycerides (mg/dl)

140.8 ± 58.0

135.0 ± 57.6

0.588

146.2 ± 70.5

0.447

HDL-cholesterol (mg/dl)

47.8 ± 14.3

49.6 ± 15.3

0.329

49 ± 15.9

0.278

LDL Cholesterol (mg/dl)

110.8 ± 35.2

109.0 ± 25.7

0.786

103.3 ± 27.2

0.521

ALP (U/l)

74.3 ± 24.6

67.4 ± 19.6

0.065

71.5 ± 22.9

0.659

ALT (U/l)

34.9 ± 15.8

29.7 ± 16.3

0.120

32.1 ± 20.6

0.315

AST (U/l)

29.4 ± 8.4

27.4 ± 8.3

0.246

29.3 ± 12.9

0.957

hs-CRP (mg/dl)

1.0 ± 1.5

0.5 ± 0.5

0.139

0.5 ± 0.7

0.156

Fasting glucose (mg/dl)

98.1 ± 15.9

103.9 ± 18.5

0.015

98 ± 14.2

0.651

Adiponectin (ng/ml)

10251.8 ± 6610

10020.2 ± 5648

0.699

10255.8 ± 5704.4

0.529

HOMA-IR

5.4 ± 4.9

4.9 ± 7.5

0.682

4.97 ± 8

0.721