What is a preferred angiotensin II receptor blocker-based combination therapy for blood pressure control in hypertensive patients with diabetic and non-diabetic renal impairment?

Table 5 Preferred antihypertensive agents based on subclinical organ damage, clinical events and comorbid conditions [6]

	ARBs	ACE inhibitors	CCBs	Diuretics	β-blockers
Uncomplicated hypertension	+	+	+	+	-
Renal dysfunction	+	+	-	-	-
ESRD/proteinuria	+	+	-	Loop diuretics	-
Metabolic syndrome	+	+	+	-	-
Diabetes mellitus	+	+	-	-	-
Isolated systolic hypertension in the elderly	-	-	+	+	-

Abbreviations: ACE = angiotensin-converting enzyme; ARBs = angiotensin II receptor blockers; CCBs = calcium channel blockers; ESRD = end-stage renal disease.

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