Table 6 Inflammatory markers, fasting glucose and triglycerides in controls and subjects with acanthosis nigricans grade 4 (Study 1, N = 100)

C-reactive protein (mg/L)

100

5.00 (0.00, 6.00)

n = 32

11.00 (6.25, 24.75)

n = 68

< 0.001

IL1 (pg/ml)

79

7.66 (0.20, 25.05)

3.17 (0.13, 12.95)

0.309

IL6 (pgml)

89

35.2 (22.2, 53.9)

30.1 (13.1, 42.8)

0.287

TNF-alpha (pg/ml)

88

8.52 (6.88, 14.00)

9.07 (8.12, 11.74)

0.603

Fasting Glucose (mg/dl)

86

79 (74, 84)

90 (77, 111)

0.011

Triglycerides (mg/dl)

87

82 (64, 104)

140 (82, 189)

< 0.001