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Table 3 The clinical characteristics and laboratory findings of patients according to the presence of CAN

From: Association of serum adipocytokine levels with cardiac autonomic neuropathy in type 2 diabetic patients

 

CAN-

CAN+

P-value

Age

51.0 ± 9.7

55.2 ± 10.2

0.021

Men/Women (%)

68/28(71/29)

26/20(56.5/43.5)

0.048

Duration of DM(year)

5.5 ± 4.7

7.5 ± 5.3

0.025

Leptin (ng/ml)

7.25 ± 7.41

8.14 ± 7.31

0.506

TNF-α (pg/ml)

1.93 ± 1.13

2.95 ± 5.51

0.220

Adiponectin (ng/ml)

3138 ± 3010

4185 ± 3615

0.072

Body mass index (kg/m2)

24.4 ± 3.6

25.0 ± 3.8

0.435

Systolic BP (mmHg)

126.3 ± 14.2

130.9 ± 15.4

0.080

Diastolic BP (mmHg)

77.6 ± 8.2

79.2 ± 9.3

0.308

HbA1C (%)

8.0 ± 2.1

7.9 ± 1.7

0.756

FPG (mg/dL)*

139 (73-377)

148 (88-340)

0.324

eGFR (mL/min/1.73m2)

81.2 ± 14.6

79.3 ± 19.0

0.531

Total cholesterol (mg/dL)

169.1 ± 31.9

167.4 ± 32.6

0.775

LDL-cholesterol (mg/dL)

96.5 ± 28.0

92.6 ± 27.2

0.438

Hypertension, n (%)

24 (25.3)

21 (46.7)

0.010

HDL-cholesterol (mg/dL)

47.6 ± 16.1

47.8 ± 13.2

0.943

Triglycerides (mg/dL)*

137 (38-1013)

121 (52-356)

0.118

hsCRP*

0.09 (0.03-6.59)

0.08 (0.03-11.42)

0.780

Apolipoprotein B (mg/dL)

79.3 ± 23.6

75.7 ± 19.3

0.462

ABI

1.11 ± 0.14

1.12 ± 0.06

0.473

PWV (cm/sec)

1488 ± 242

1575 ± 252

0.050

HOMA-IR*

2.58 (0.09-15.82)

2.87 (0.55-29.01)

0.016

Smoking (%)

32 (33.3)

15 (32.6)

0.545

Alcohol (%)

38 (39.6)

24 (52.2)

0.088

Treatment modality

  

0.131

No medication

27 (28.1)

5(11.1)

 

OHA (n/%)

63 (65.6)

34 (75.6)

 

OHA + Insulin (n/%)

3 (3.1)

2 (4.4)

 

Insulin (n/%)

3 (3.1)

4 (8.9)

 
  1. Data are shown as mean ± SD, or as n (%). BMI: Body mass index; FPG: fasting plasma glucose; HbA1C: hemoglobin A1C; eGFR: estimated glomerular filtration rate; LDL: Low density lipoprotein; HDL: high density lipoprotein; OHA: oral hypoglycemic agent *Natural logarithmic transformations were performed before analysis