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Table 3 The clinical characteristics and laboratory findings of patients according to the presence of CAN

From: Association of serum adipocytokine levels with cardiac autonomic neuropathy in type 2 diabetic patients

  CAN- CAN+ P-value
Age 51.0 ± 9.7 55.2 ± 10.2 0.021
Men/Women (%) 68/28(71/29) 26/20(56.5/43.5) 0.048
Duration of DM(year) 5.5 ± 4.7 7.5 ± 5.3 0.025
Leptin (ng/ml) 7.25 ± 7.41 8.14 ± 7.31 0.506
TNF-α (pg/ml) 1.93 ± 1.13 2.95 ± 5.51 0.220
Adiponectin (ng/ml) 3138 ± 3010 4185 ± 3615 0.072
Body mass index (kg/m2) 24.4 ± 3.6 25.0 ± 3.8 0.435
Systolic BP (mmHg) 126.3 ± 14.2 130.9 ± 15.4 0.080
Diastolic BP (mmHg) 77.6 ± 8.2 79.2 ± 9.3 0.308
HbA1C (%) 8.0 ± 2.1 7.9 ± 1.7 0.756
FPG (mg/dL)* 139 (73-377) 148 (88-340) 0.324
eGFR (mL/min/1.73m2) 81.2 ± 14.6 79.3 ± 19.0 0.531
Total cholesterol (mg/dL) 169.1 ± 31.9 167.4 ± 32.6 0.775
LDL-cholesterol (mg/dL) 96.5 ± 28.0 92.6 ± 27.2 0.438
Hypertension, n (%) 24 (25.3) 21 (46.7) 0.010
HDL-cholesterol (mg/dL) 47.6 ± 16.1 47.8 ± 13.2 0.943
Triglycerides (mg/dL)* 137 (38-1013) 121 (52-356) 0.118
hsCRP* 0.09 (0.03-6.59) 0.08 (0.03-11.42) 0.780
Apolipoprotein B (mg/dL) 79.3 ± 23.6 75.7 ± 19.3 0.462
ABI 1.11 ± 0.14 1.12 ± 0.06 0.473
PWV (cm/sec) 1488 ± 242 1575 ± 252 0.050
HOMA-IR* 2.58 (0.09-15.82) 2.87 (0.55-29.01) 0.016
Smoking (%) 32 (33.3) 15 (32.6) 0.545
Alcohol (%) 38 (39.6) 24 (52.2) 0.088
Treatment modality    0.131
No medication 27 (28.1) 5(11.1)  
OHA (n/%) 63 (65.6) 34 (75.6)  
OHA + Insulin (n/%) 3 (3.1) 2 (4.4)  
Insulin (n/%) 3 (3.1) 4 (8.9)  
  1. Data are shown as mean ± SD, or as n (%). BMI: Body mass index; FPG: fasting plasma glucose; HbA1C: hemoglobin A1C; eGFR: estimated glomerular filtration rate; LDL: Low density lipoprotein; HDL: high density lipoprotein; OHA: oral hypoglycemic agent *Natural logarithmic transformations were performed before analysis