Table 1 Baseline characteristics for cases with incident type 2 diabetes mellitus and referents
Total population | |||||
|---|---|---|---|---|---|
n | Cases | n | Referents | p-value | |
Time to T2DM diagnosis, years | 157 | 5.5 ± 2.7 | - | - | - |
Age, years | 157 | 50.5 ± 8.1 | 277 | 50.2 ± 8.3 | matched |
Sex, male (%) | 157 | 56.7 | 277 | 56.7 | matched |
Family history of T2DM, n (%) | 154 | 48 (31.4) | 269 | 44 (16.4) | < 0.001 |
Non, Ex, Daily smoking, n (%) | 156 | 56 (35.9), 56 (35.9), 44 (28.2) | 272 | 112 (41.2) 105 (38.6) 55 (20.2) | 0.163 |
Sedentary, Moderate, Active, n (%) | 157 | 23 (14.6), 116 (73.9), 18 (11.5) | 277 | 48 (17.3), 190 (68.6), 39 (14.1) | 0.507 |
Hypertension*, n (%) | 157 | 104 (66.2) | 277 | 39 (32.1) | < 0.001 |
Antihypertensive medication, n (%) | 157 | 41 (26.1) | 277 | 16 (5.8) | < 0.001 |
Systolic blood pressure, mmHg | 157 | 139.2 ± 18.3 | 276 | 127.5 ± 16.8 | < 0.001 |
Diastolic blood pressure, mmHg | 157 | 87.0 ± 12.5 | 276 | 79.7 ± 10.4 | < 0.001 |
Fasting plasma glucose, mmol/L | 157 | 5.9 ± 0.8 | 277 | 5.2 ± 0.7 | < 0.001 |
2-h plasma glucose, mmol/L | 157 | 8.2 ± 2.1 | 277 | 6.5 ± 1.7 | < 0.001 |
BMI, kg/m2 | 156 | 29.5 ± 4.2 | 277 | 25.3 ± 3.6 | < 0.001 |
Total cholesterol, mmol/L | 157 | 6.0 ± 1.0 | 277 | 5.7 ± 1.0 | < 0.001 |
HDL, mmol/L | 157 | 1.1 ± 0.3 | 277 | 1.3 ± 0.3 | 0.002 |
Triglycerides, mmol/L | 157 | 1.7 (1.3 - 2.5) | 277 | 1.1 (0.9 - 1.6) | < 0.001 |
tPA, ng/mL | 156 | 11.0 (8.7 - 13.7) | 276 | 7.7 (5.6 - 10.5) | < 0.001 |
PAI-1, ng/mL | 157 | 35.0 (23.9 - 46.1) | 276 | 21.2 (14.6 - 31.3) | < 0.001 |
tPA/PAI-1 complex, ng/mL | 155 | 7.9 (5.2 - 0.4) | 277 | 3.8 (2.5 - 5.8) | < 0.001 |
VWF, % | 156 | 142.9 (119.1 - 178.9) | 276 | 124.0 (96.0 - 159.6) | < 0.001 |