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Table 5 Odds for prevalent metabolic syndrome, metabolic syndrome components and atherogenic dyslipidemia according to levels of PTH and 25(OH)D

From: Plasma vitamin D and parathormone are associated with obesity and atherogenic dyslipidemia: a cross-sectional study

Dependent variable

Model I

Model 2

Model 3

Model 4

Explanatory variables

OR (95% CI)

P*

OR (95% CI)

P*

OR (95% CI)

P*

OR (95% CI)

P*

Metabolic syndrome

        

 PTH

1.13 (1.01, 1.26)

0.027

1.10 (0.98, 1.24)

0.090

0.93 (0.81, 1.07)

0.309

0.99 (0.83, 1.17)

0.880

 25(OH)

0.99 (0.98, 1.00)

0.004

0.99 (0.98, 1.00)

0.004

1.00 (0.99, 1.01)

0.825

1.00 (0.99, 1.02)

0.690

 Age

  

1.02 (1.00, 1.05)

0.027

1.04 (1.01, 1.07)

0.005

1.04 (1.01, 1.08)

0.011

 BMI

    

1.20 (1.14, 1.26)

<0.001

1.21 (1.13, 1.30)

<0.001

Elevated blood pressure

        

 PTH

1.40 (1.17, 1.68)

<0.001

1.26 (1.03, 1.54)

0.027

1.10 (0.88, 1.39)

0.409

1.15 (0.88, 1.51)

0.297

 25(OH)D

1.00 (0.99, 1.00)

0.219

0.99 (0.98, 1.00)

0.141

1.00 (0.99, 1.01)

0.677

1.00 (0.98, 1.01)

0.825

 Age

  

1.07 (1.04, 1.10)

<0.001

1.06 (1.03, 1.10)

<0.001

1.03 (0.99, 1.07)

0.117

 BMI

    

1.13 (1.06, 1.20)

<0.001

1.14 (1.05, 1.23)

0.002

Reduced HDL cholesterol

        

 PTH

1.13 (1.01, 1.27)

0.031

1.16 (1.03, 1.31)

0.015

1.05 (0.92, 1.19)

0.446

1.07 (0.93, 1.24)

0.352

 25(OH)D

0.99 (0.98, 0.99)

0.001

0.99 (0.98, 0.99)

0.001

0.99 (0.99, 1.00)

0.180

1.00 (0.98, 1.01)

0.618

 BMI

    

1.11 (1.07, 1.16)

<0.001

1.09 (1.04, 1.14)

<0.001

Elevated fasting triglycerides

        

 PTH

0.93 (0.84, 1.04)

0.208

0.92 (0.82, 1.03)

0.136

0.90 (0.80, 1.01)

0.080

0.86 (0.74, 1.00)

0.051

 25(OH)D

0.99 (0.98, 1.00)

0.037

0.99 (0.98, 1.00)

0.024

0.99 (0.98, 1.00)

0.060

0.98 (0.97, 1.00)

0.026

 Calcium Tertile 1

0.50 (0.26, 0.97)

0.045

0.52 (0.26, 1.05)

0.068

0.53 (0.27, 1.08)

0.079

0.71 (0.30, 1.65)

0.423

     Tertile 2

0.51 (0.27, 0.97)

0.040

0.51 (0.26, 0.99)

0.047

0.50 (0.25, 0.97)

0.041

1.00 (0.45, 2.22)

0.998

Diabetes

        

 PTH

1.10 (0.99, 1.22)

0.072

1.02 (0.91, 1.15)

0.733

0.93 (0.82, 1.06)

0.270

0.94 (0.82, 1.01)

0.420

 25(OH)D

0.99 (0.99, 1.00)

0.078

0.99 (0.99, 1.00)

0.023

1.00 (0.99, 1.00)

0.449

1.00 (0.99, 1.01)

0.787

 Calcium Tertile 1

0.35 (0.19, 0.66)

0.001

0.41 (0.20, 0.84)

0.014

0.45 (0.22, 0.93)

0.032

0.46 (0.19, 1.09)

0.079

     Tertile 2

0.44 (0.24, 0.80)

0.008

0.48 (0.24, 0.94)

0.034

0.43 (0.21, 0.88)

0.021

0.48 (0.20, 1.12)

0.088

 Age

  

1.07 (1.05, 1.10)

<0.001

1.09 (1.06, 1.12)

<0.001

1.10 (1.06, 1.14)

<0.001

 BMI

    

1.09 (1.05, 1.13)

<0.001

1.07 (1.02, 1.12)

0.005

Atherogenic dyslipidemia

        

 PTH

1.22 (1.07, 1.40)

0.004

1.18 (1.02, 1.36)

0.022

1.07 (0.92, 1.25)

0.345

1.02 (0.87, 1.20)

0.798

 25(OH)D

0.99 (0.98, 0.99)

<0.001

0.99 (0.98, 0.99)

<0.001

0.99 (0.98, 1.00)

0.032

0.99 (0.98, 1.01)

0.407

 Calcium Tertile 1

0.36 (0.16, 0.80)

0.012

0.41 (0.18, 0.92)

0.032

0.41 (0.17, 0.96)

0.040

0.50 (0.19, 1.29)

0.153

     Tertile 2

0.41 (0.19, 0.87)

0.021

0.43 (0.19, 0.93)

0.033

0.34 (0.14, 0.80)

0.014

0.46 (0.18, 1.17)

0.102

 BMI

    

1.09 (1.05, 1.14)

<0.001

1.11 (1.05, 1.17)

<0.001

  1. *P value by multiple logistic regression analysis.
  2. PTH: Parathormone; 25(OH)D: 25.Hydroxy-cholecalcipherol; BMI: Body mass index.
  3. Model 1. Explanatory variables in the multiple logistic regression model were PTH, 25(OH)D and tertiles of calcium.
  4. Model 2. Explanatory variables as in model 1 plus age, gender, season and current smoking.
  5. Model 3. Explanatory variables as in model 2 plus BMI.
  6. Model 4. Explanatory variables as in model 3 plus uCRP and leukocyte count.
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Cardiovascular Diabetology

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