| Liraglutide added (n=42) | Insulin increasing (n=42) | P |
---|---|---|---|
Age (years) | 51.2 ± 10.5 | 52.7 ± 10.8 | NS |
Sex (M/F) |     26/16 |     24/18 | NS |
Duration of diabetes (years) |   9.1 ± 3.6 |   8.9± 3.6 | NS |
Body weight (kg) | 88.6 ± 11.8 | 86.3 ± 10.3 | NS |
BMI (kg/m2) |   30.4 ± 3.2 |   30.3 ± 3.0 | NS |
Waist Circumference (cm) | 105.6 ± 12.6 | 104.6 ± 10.5 | NS |
Systolic blood pressure (mmHg) | |||
FBG (mmol/L) |  8.36 ± 0.93 |  8.41 ± 0.86 | NS |
P2BG (mmol/L) | 13.76 ± 1.92 | 13.80 ± 1.96 | NS |
HbA1c (%) |  8.79 ± 0.86 |  8.69 ± 0.91 | NS |
Oral antidiabetic agents | |||
Sulfonylurea |  7 (16.7%) |  9 (21.4%) | NS |
Thiazolidinedione | 17 (40.5%) | 14 (33.3%) | NS |
α-glucosidase inhibitors |   15 (35.7) | 13 (31.0%) | NS |
Glinides | 16 (38.1%) | 13 (31.0%) | NS |
Metformin | 25 (59.5%) | 27 (64.3%) | NS |
Insulin regimen | Â | Â | Â |
Total daily insulin dose (units/day) | 41.2 ± 17.4 | 41.6 ± 16.5 | NS |
Insulin glargine only | 11 (26.2%) | 13 (31.0%) | NS |
Insulin NPH only | 18 (42.9%) | 14 (33.3%) | NS |
Premixed insulin | 13 (31.0%) | 15 (35.7%) | NS |