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Table 1 Characteristics of the patients at baseline

From: Efficacy and safety comparison between liraglutide as add-on therapy to insulin and insulin dose-increase in Chinese subjects with poorly controlled type 2 diabetes and abdominal obesity

 

Liraglutide added (n=42)

Insulin increasing (n=42)

P

Age (years)

51.2 ± 10.5

52.7 ± 10.8

NS

Sex (M/F)

    26/16

    24/18

NS

Duration of diabetes (years)

  9.1 ± 3.6

  8.9± 3.6

NS

Body weight (kg)

88.6 ± 11.8

86.3 ± 10.3

NS

BMI (kg/m2)

  30.4 ± 3.2

  30.3 ± 3.0

NS

Waist Circumference (cm)

105.6 ± 12.6

104.6 ± 10.5

NS

Systolic blood pressure (mmHg)

FBG (mmol/L)

 8.36 ± 0.93

 8.41 ± 0.86

NS

P2BG (mmol/L)

13.76 ± 1.92

13.80 ± 1.96

NS

HbA1c (%)

 8.79 ± 0.86

 8.69 ± 0.91

NS

Oral antidiabetic agents

Sulfonylurea

 7 (16.7%)

 9 (21.4%)

NS

Thiazolidinedione

17 (40.5%)

14 (33.3%)

NS

α-glucosidase inhibitors

  15 (35.7)

13 (31.0%)

NS

Glinides

16 (38.1%)

13 (31.0%)

NS

Metformin

25 (59.5%)

27 (64.3%)

NS

Insulin regimen

   

Total daily insulin dose (units/day)

41.2 ± 17.4

41.6 ± 16.5

NS

Insulin glargine only

11 (26.2%)

13 (31.0%)

NS

Insulin NPH only

18 (42.9%)

14 (33.3%)

NS

Premixed insulin

13 (31.0%)

15 (35.7%)

NS

  1. Data are expressed as mean ± S.D. or frequency [n (%)], BMI: body mass index; FBG: fasting blood glucose; P2BG: 2-hour postprandial blood glucose; HbA1c: glycosylated haemoglobin A1c; NS: not significant.