Skip to main content

Table 6 Cardiac element content and select gene expression at 6 wks after injection of STZ (HG) or vehicle (nonHG) in hypothyroid rats fed PTU diet or in euthyroid rats fed standard rat chow

From: Zinc-induced cardiomyocyte relaxation in a rat model of hyperglycemia is independent of myosin isoform

  Hypothyroid Euthyroid
   HG (n=8)  nonHG (8) HG (6) nonHG (6)
Ca 101.2 ± 6.0 100.8 ± 7.4 284.4 ± 44.3* 155.4 ± 32.9
Cu 4.4 ± 0.2 3.9 ± 0.2 5.2 ± 0.3 * 6.4 ± 0.2
Fe 66.7 ± 3.0* 58.7 ± 1.9 95.5 ± 2.5 † 122.3 ± 7.5
K 2316 ± 148 2053 ± 85 7369 ± 793 * 5052 ± 566
Mg 186.8 ± 8.9 177.3 ± 7.6 275.1 ± 13.6 257.8 ± 6.0
Na 1863 ± 102 1788 ± 75 2325 ± 224 * 1641 ± 186
P 2158 ± 105 2012 ± 81 2726 ± 86 2711 ± 24
S 2545±155 * 2022 ± 102 3707 ± 163* 3149 ± 95
Zn 17.6 ± 0.7 17.7 ± 0.8 23.1 ± 1.1 22.2 ± 0.3
MT1a - - 0.66 ± 0.13 * 1.00 ± 0.05
ZnT2 - - 0.76 ± 0.07 # 1.00 ± 0.10
γ-GCSh - - 1.30 ± 0.08 † 1.00 ± 0.03
  1. Concentration given in ppm: μg of element per g wet weight of LV. Gene expression given in RQ = 2-ΔΔCt. normalized to HPRT expression and then to mean of nonHG. Differences between HG and nonHG controls reported at *P<0.05, †P<0.01.