Men | Quartiles | ||||
---|---|---|---|---|---|
 | Q1 (lowest) | Q2 | Q3 | Q4 (highest) | P for trend* |
Testosterone (ng/mL) | |||||
Median (range) | 3.04 (0.06–3.84) | 4.42 (3.85–4.88) | 5.44 (4.90–6.20) | 6.96 (6.21–12.80) |  |
(cases/controls) | 69/39 | 54/55 | 49/56 | 43/64 | Â |
Model 1†| 1.00 | 0.55 (0.31–0.98) | 0.48 (0.27–0.84) | 0.37 (0.21–0.66) | <0.001 |
Model 2‡ | 1.00 | 0.72 (0.38–1.37) | 0.62 (0.32–1.20) | 0.44 (0.23–0.84) | 0.01 |
Model 3§ | 1.00 | 0.66 (0.34–1.29) | 0.64 (0.33–1.26) | 0.45 (0.23–0.89) | 0.03 |
Model 4|| | 1.00 | 0.64 (0.32–1.30) | 0.63 (0.29–1.34) | 0.40 (0.18–0.88) | 0.03 |
SHBG (nmol/L) | |||||
Median (range) | 42.1 (16.8–52.4) | 62.2 (52.5–72.4) | 81.8 (72.5–93.6) | 112.0 (93.8–161.0) |  |
(cases/controls) | 58/50 | 55/54 | 55/52 | 47/59 | Â |
Model 1†| 1.00 | 0.87 (0.50–1.51) | 0.87 (0.50–1.54) | 0.67 (0.38–1.18) | 0.17 |
Model 2‡ | 1.00 | 0.81 (0.43–1.51) | 1.04 (0.55–2.00) | 0.73 (0.38–1.40) | 0.44 |
Model 3§ | 1.00 | 0.85 (0.44–1.64) | 1.15 (0.59–2.24) | 0.79 (0.41–1.53) | 0.59 |
Model 4|| | 1.00 | 1.04 (0.52–2.10) | 1.55 (0.73–3.27) | 1.22 (0.56–2.67) | 0.54 |
Women | |||||
Testosterone (ng/mL) | |||||
Median (range) | 0.08 (0.04–0.10) | 0.13 (0.11–0.15) | 0.19 (0.16–0.22) | 0.27 (0.23–0.48) |  |
(cases/controls) | 20/24 | 19/22 | 22/21 | 21/14 | Â |
Model 1†| 1.00 | 1.09 (0.49–2.47) | 1.33 (0.55–3.17) | 1.83 (0.76–4.40) | 0.17 |
Model 2‡ | 1.00 | 0.76 (0.22–2.69) | 1.05 (0.29–3.81) | 1.90 (0.54–6.68) | 0.27 |
Model 3§ | 1.00 | 0.72 (0.20–2.62) | 0.97 (0.25–3.79) | 2.02 (0.54–7.54) | 0.25 |
Model 4|| | 1.00 | 0.74 (0.13–4.09) | 2.82 (0.36–22.10) | 9.20 (0.80–105.15) | 0.046 |
SHBG (nmol/L) | |||||
Median (range) | 49.5 (12.9–60.8) | 76.6 (61.3–89.4) | 105.0 (89.5–124.0) | 139.5 (125.0–163.0) |  |
(cases/controls) | 33/10 | 20/22 | 20/23 | 12/30 | Â |
Model 1†| 1.00 | 0.35 (0.13–0.91) | 0.32 (0.13–0.78) | 0.15 (0.05–0.40) | <0.001 |
Model 2‡ | 1.00 | 0.17(0.03–0.91) | 0.19 (0.05–0.79) | 0.12 (0.02–0.86) | 0.03 |
Model 3§ | 1.00 | 0.18 (0.03–0.98) | 0.20 (0.05–0.87) | 0.13 (0.02–0.96) | 0.048 |
Model 4|| | 1.00 | 0.21 (0.02–2.78) | 0.23 (0.03–1.93) | 0.03 (0.001–0.86) | 0.06 |