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Table 2 Cardiovascular risk profiles according to quintiles of UACR in women

From: Higher normal ranges of urine albumin-to-creatinine ratio are independently associated with carotid intima-media thickness

 

UACR, mg/g

p*

 

< 6.50

6.5-9.79

9.80-13.49

13.50-18.89

≥ 18.90

 

Number (%)

798 (17.8)

839 (18.8)

882 (19.7)

928 (20.8)

1024 (22.9)

 

Age, y

56.8 ± 7.8

58.8 ± 7.9

60.2 ± 7.7

62.0 ± 7.3

62.9 ± 7.3

< 0.001

Current smoker, %

3.4

4.5

2.3

4.0

2.8

0.371

Current drinker, %

38.8

41.1

34.8

35.0

36.8

0.054

Hypertension, %

24.8

27.7

31.6

33.5

42.9

< 0.001

Type 2 diabetes, %

5.1

5.5

7.2

8.3

9.8

< 0.001

Hyperlipidemia, %

11.8

11.5

11.1

12.9

12.4

0.441

Body mass index, kg/m2

24.5 ± 3.0

24.6 ± 3.0

24.6 ± 3.2

24.5 ± 3.1

24.5 ± 3.2

0.969

Waist circumference, cm

86.4 ± 7.9

86.4 ± 8.4

86.4 ± 8.7

86.1 ± 8.8

86.0 ± 8.9

0.714

Systolic BP, mmHg

117.8 ± 16.0

119.6 ± 16.0

121.5 ± 16.7

123.6 ± 17.2

127.2 ± 18.6

< 0.001

Diastolic BP, mmHg

77.2 ± 9.4

77.4 ± 9.0

78.5 ± 9.4

79.4 ± 9.5

80.6 ± 10.8

< 0.001

Total cholesterol, mmol/L

4.9 ± 1.0

4.9 ± 0.9

5.0 ± 0.9

5.0 ± 0.9

5.0 ± 1.0

0.139

Triglycerides, mmol/L

1.5 ± 1.0

1.5 ± 1.0

1.6 ± 1.0

1.7 ± 1.0

1.7 ± 1.4

< 0.001

HDL cholesterol, mmol/L

1.3 ± 0.3

1.3 ± 0.3

1.2 ± 0.3

1.2 ± 0.3

1.3 ± 0.3

0.400

FBG, mmol/L

5.5 ± 0.7

5.5 ± 0.8

5.5 ± 0.8

5.5 ± 1.0

5.6 ± 1.0

0.001

HOMA-IR

1.4 ± 0.9

1.4 ± 1.3

1.4 ± 1.1

1.4 ± 1.1

1.4 ± 1.2

0.449

Serum creatinine, μmol/L

70.8 ± 9.6

70.2 ± 10.1

68.6 ± 11.5

67.4 ± 9.6

68.1 ± 10.9

< 0.001

eGFR, ml/min/1.73m2

83.8 ± 12.7

84.1 ± 13.0

86.0 ± 14.9

86.2 ± 13.3

85.6 ± 14.5

< 0.001

  1. Data are expressed as mean ± standard deviation, unless otherwise indicated.
  2. * p-values for analysis of variance (ANOVA) and chi-square tests for trends are shown, as appropriate.