Liraglutide (n=29) | Insulin (n=28) | P value | |
---|---|---|---|
Males/females | 12/17 | 14/14 | 0.514 |
Age (years) | 58.1 ± 12.1 | 63.9 ± 12.2 | 0.080 |
Duration of diabetes (years) | 16.0 ± 8.3 | 18.5 ± 10.0 | 0.309 |
Body weight (kg) | 82.0 ± 16.2 | 76.6 ± 15.5 | 0.122 |
Body mass index (kg/m2) | 31.3 ± 5.3 | 29.1 ± 3.0 | 0.102 |
HbA1c (%) | 8.5 ± 1.4 | 9.4 ± 1.6 | 0.023 |
Fasting plasma glucose (mg/dL) | 159.0 ± 49.7 | 156.4 ± 59.2 | 0.655 |
Fasting C-peptide (mg/dL) | 2.09 ± 0.97 | 1.97 ± 0.24 | 0.267 |
Low-density lipoprotein-cholesterol (mg/dL) | 113.1 ± 36.5 | 116.6 ± 28.2 | 0.689 |
High-density lipoprotein-cholesterol (mg/dL) | 44.2 ± 8.1 | 46.1 ± 13.8 | 0.534 |
Triglycerides (mg/dL) | 149.4 ± 55.2 | 201.2 ± 145.0 | 0.432 |
Hypertension (%) | 83 | 86 | 0.760 |
Dyslipidemia (%) | 90 | 86 | 0.650 |
Previous treatment | |||
Biguanide (%) | 38 | 18 | 0.092 |
Sulfonylurea (%) | 31 | 21 | 0.410 |
Alpha-glucosidase inhibitor (%) | 17 | 29 | 0.308 |
Thiazolidinedione (%) | 21 | 14 | 0.525 |
DPP-IV inhibitor (%) | 10 | 7 | 0.669 |
Glinide (%) | 3 | 0 | 0.322 |
Insulin (%) | 55 | 82 | 0.029 |