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Table 4 Changes of echocardiographic data pre- and post-treatment of OLETF rats fed on sucrose contained water

From: Effects of granulocyte-colony stimulating factor (G-CSF) on diabetic cardiomyopathy in Otsuka Long-Evans Tokushima Fatty rats

 

OLETF (+/-)

OLETF (+/+)

 

Pre-

treatment

Post-

treatment

p

Pre-

treatment

Post-

treatment

p

E (cm/sec)

68.7 ± 6.1

70.1 ± 1.4

0.611

62.4 ± 1.8

73.9 ± 3.3

0.001

E' (cm/sec)

5.3 ± 0.3

4.7 ± 0.1

0.006

5.2 ± 0.3

6.6 ± 0.2

0.001

E/E'

13.0 ± 0.5

15.0 ± 0.7

0.001

12.0 ± 0.6

11.3 ± 0.8

0.224

  1. Values are mean ± SD.
  2. OLETF; Otsuka Long-Evans Tokushima Fatty rat, G-CSF; granulocyte-colony stimulating factor, E; peak velocity of the early diastolic filling wave, E'; early mitral annulus velocity
  3. OLETF (+/-); OLETF rats fed on sucrose water and treated with saline,
  4. OLETF (+/+); OLETF rats fed on sucrose water and treated with G-CSF