| OLETF (+/-) | OLETF (+/+) |
---|
| Pre- treatment | Post- treatment | p | Pre- treatment | Post- treatment | p |
---|
E (cm/sec)
|
68.7 ± 6.1
|
70.1 ± 1.4
|
0.611
|
62.4 ± 1.8
|
73.9 ± 3.3
|
0.001
|
E' (cm/sec)
|
5.3 ± 0.3
|
4.7 ± 0.1
|
0.006
|
5.2 ± 0.3
|
6.6 ± 0.2
|
0.001
|
E/E'
|
13.0 ± 0.5
|
15.0 ± 0.7
|
0.001
|
12.0 ± 0.6
|
11.3 ± 0.8
|
0.224
|
- Values are mean ± SD.
- OLETF; Otsuka Long-Evans Tokushima Fatty rat, G-CSF; granulocyte-colony stimulating factor, E; peak velocity of the early diastolic filling wave, E'; early mitral annulus velocity
- OLETF (+/-); OLETF rats fed on sucrose water and treated with saline,
- OLETF (+/+); OLETF rats fed on sucrose water and treated with G-CSF