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Table 3 Data of LETO rats and OLETF rats fed on sucrose contained water at the time of 22 weeks old (4 weeks after G-CSF or saline treatment)

From: Effects of granulocyte-colony stimulating factor (G-CSF) on diabetic cardiomyopathy in Otsuka Long-Evans Tokushima Fatty rats

 

LETO (-)

(n = 8)

OLETF (+/-)

(n = 6)

OLETF (+/+)

(n = 6)

p

BW (g)

444.0 ± 15.2

624.0 ± 23.8*

598.7 ± 50.8*

< 0.001

FBG (mg/dl)

210.8 ± 46.6

367.3 ± 47.9*

314.0 ± 56.2*

< 0.001

TC (mg/dl)

55.4 ± 6.9

58.5 ± 9.7

54.2 ± 16.5

0.790

TG (mg/dl)

45.9 ± 12.5

116.3 ± 16.4*

128.2 ± 55.9**

< 0.001

HR (bpm)

292.9 ± 18.1

291.7 ± 35.5

289.5 ± 18.6

0.968

E (cm/sec)

79.5 ± 4.2

70.1 ± 1.4*

73.9 ± 3.3**

0.001

E' (cm/sec)

7.1 ± 0.5

4.7 ± 0.1*

6.6 ± 0.2†

< 0.001

E/E'

11.2 ± 0.6

15.0 ± 0.7*

11.3 ± 0.8†

< 0.001

DT (msec)

76.4 ± 5.5

69.3 ± 7.7

72.0 ± 4.0

0.105

BP (mmHg)

160.0 ± 14.1

166.9 ± 2.0

177.0 ± 21.9

0.587

  1. Values are mean ± SD. *p < 0.01 and **p < 0.05 versus LETO (-). †p < 0.01 and ‡p < 0.05 versus OLETF (+/-).
  2. LETO; Long-Evans Tokushima Otsuka rat, OLETF; Otsuka Long-Evans Tokushima Fatty rat, G-CSF; granulocyte-colony stimulating factor, BW; body weight, FBG; fasting blood glucose, TC; total cholesterol, TG; triglyceride, HR; heart rate, E; peak velocity of the early diastolic filling wave, E'; early mitral annulus velocity, DT; deceleration time, BP; blood pressure,
  3. LETO (-); LETO rats fed on tap water,
  4. OLETF (+/-); OLETF rats fed on sucrose water and treated with saline,
  5. OLETF (+/+); OLETF rats fed on sucrose water and treated with G-CSF
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Cardiovascular Diabetology

ISSN: 1475-2840