Table 1 Clinical, ergometric and scintigraphic characteristics of subjects included in the study
Diabetic Patients | Controls | ||
|---|---|---|---|
n = 41 | n = 41 | p | |
Age (years) | 63.0 ± 5.4 | 61.1 ± 6.1 | 0.1 |
Male/Female (n) | 11/30 | 11/30 | 0.59 |
Obesitya (%) | 48.8% | 34.14% | 0.26 |
Smokingb (%) | 19.5% | 21.9% | 0.95 |
Hypertensionc (%) | 56% | 36.6% | 0.12 |
Dyslipemiad (%) | 73.1% | 63.4% | 0.33 |
Family history of CADe (%) | 14.6% | 17.1% | 0.5 |
Duration of diabetes (years) | 11.0 ± 7.2 | - | |
Retinopathy (%) | 17.1% | - | |
Nephropathy (%) | 9.7% | - | |
Neuropathy (%) | 2.4% | - | |
Laboratory parameters: | |||
Glucose (mg/dl) | 162 ± 6 | 98 ± 9 | <0.001 |
HbA1c (%) | 8.2 ±1.3 | 5.8 ± 0.1 | <0.001 |
AER (μg/minute) | 6 [2-44] | 5 [2-26] | 0.73 |
Total-C (mg/dl) | 206 ± 45 | 228 ± 39 | 0.06 |
HDL-C (mg/dl) | 56 ± 10 | 55 ± 10 | 0.71 |
LDL-C (mg/dl) | 121 ± 38 | 167 ± 19 | <0.001 |
Triglycerides (mg/dl) | 139 [65-242] | 125 [66-175] | 0.24 |
Exercise test: | |||
METs | 6.74 ± 2.01 | 7.01 ± 1.78 | 0.60 |
Peak heart rate (bpm) | 136 ± 14 | 138 ± 14 | 0.54 |
Peak systolic blood pressure (mmHg) | 179 ± 24 | 172 ± 17 | 0.25 |
Gated-SPECT: | |||
Ejection fraction (%) | 74.3 ± 11.1 | 72.6 ± 8.1 | 0.51 |
LV end-diastolic volume (ml) | 57.6 ± 17.9 | 64.6 ± 14.6 | 0.12 |
LV end-systolic volume (ml) | 16.4 ± 11.8 | 19.4 ± 8.6 | 0.30 |