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Table 1 Clinical and Metabolic Characteristics of Study Population

From: Circulating endothelial progenitor cells and large artery structure and function in young subjects with uncomplicated Type 1 Diabetes

 

Controls

T1DM

p

N

26

16

 

Sex (males, %)

58

68

= 0.47

Age (years)

19 ± 2

18 ± 2

= 0.12

Body mass index (kg/m2)

21.6 ± 4.2

21.7 ± 6.2

= 0.82

Systolic BP (mmHg)

112 ± 10

118 ± 16

= 0.13

Diastolic BP (mmHg)

67 ± 5

66 ± 7

= 0.94

Mean BP (mmHg)

82 ± 5

83 ± 8

= 0.47

Heart rate (bpm)

70 ± 12

69 ± 11

= 0.88

Total cholesterol (mg/dL)

165 ± 22

170 ± 33

= 0.37

HDL-cholesterol (mg/dL)

58 ± 13

54 ± 8

= 0.36

LDL-cholesterol (mg/dL)

87 ± 19

100 ± 21

= 0.08

∫Triglycerides (mg/dL)

71 [31]

75 [25]

= 0.94

∫Adiponectin (mg/L)

18.5 [5.5]

19.0 [4.5]

= 0.09

Fasting plasma glucose (mg/dL)

87 ± 7

178 ± 45

< 0.0001

sRAGEs (pg/ml)

383 ± 152

464 ± 187

= 0.76

AGE-dependent AF (arbitrary units)

1.6 ± 0.3

1.7 ± 0.3

= 0.52

∫ EPCs (CD34+/KDR+/10 6 events*)

74 [150]

39 [63]

= 0.02

  1. ∫: skewed variables expressed as median [interquartile] range; * EPCs: log-transformed endothelial progenitor cells expressed as CD34+/KDR+ cells/106 cytometric events; p values after adjustment for sex and age. Statistically significant differences are highlighted in bold italic.