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Table 2 The relationship between IHD, CVA and clinical variables

From: Age, gender, insulin and blood glucose control status alter the risk of ischemic heart disease and stroke among elderly diabetic patients

IHD = < 70 y.o.

Mean(SD)

Hgb A1C = < 7.0 (Gp.MF)

7.0 < HgbA1C (Gp.MP)

Number of events

 

17

15

  

Univariate

Multivariate

Univariate

Multivariate

Male/Female

0.96

0.75 (0.40-1.37)

 

1.03 (0.62-1.74)

 

Age (y.o.)

60.9(7.9)y.o.

1.06 (0.98-1.20)

 

1.03 (0.96-1.13)

 

Duration of diabetes (years)

9.15(8.22)

1.04+ (0.99-1.09)

 

1.03 (0.96-1.08)

 

Hemoglobin A1C(%)

7.38(1.31)

1.16 (0.40-4.37)

 

1.01 (0.60-1.50)

 

Triglyceride (mg/dl)

146.9(129.5)

1.01 (0.99 - 1.03)

 

1.01 (0.94-1.04)

 

LDL-Chol (mg/dl)

119.2(34.1)

1.13* (1.01-1.28)

1.12 + (1.00-1.28)

1.04 (0.87-1.21)

 

HDL-Chol (mg/dl)

55.4(16.2)

0.54* (0.29-0.91)

0.46*(0.26-0.85)

0.78 (0.53-1.08)

 

Systolic BP(mmHg)

133.5(17.5)

1.58* (1.11-2.24)

1.81**(1.19-2.93)

1.07 (0.80-1.49)

 

Diastolic BP (mmHg)

75.5(11.7)

0.94 (0.63-1.58)

 

0.96 (0.63-1.62)

 

Insulin user (%)

32.80%

0.96 (0.37-1.93)

 

1.06 (0.61-1.81)

 

IHD 70 < y.o.

Mean(SD)

Hgb A1C = < 7.0 (Gp.OF)

7.0 < HgbA1C (Gp.OP)

Number of events

 

25

25

  

Univariate

Multivariate

Univariate

Multivariate

Male/Female

1

1.12 (0.71-1,81)

 

1.41 (0.83-2.97)

 

Age (y.o.)

75.4(4.3)

0.99 (0.88-1.09)

 

0.83 (0.66-0.99)

 

Duration of diabetes (years)

10.18(9.08)

1.02 (0.98-1.06)

 

1.02 (0.93-1.08)

 

Hemoglobin A1C (%)

7.26 (1.15)

1.74 (0.65-5.55)

 

1.37 (0.77-2.16)

 

Triglyceride (mg/dl)

129.2 (62.2)

1.00 (1.00-1.09)

 

1.01 (0.99-1.04)

 

LDL-Chol (mg/dl)

116.1 (30.6)

0.99 (0.78-1.11)

 

1.05 (0.87-1.24)

 

HDL-Chol (mg/dl)

54.7 (16.2)

0.99 (0.73-1.26)

 

0.79 (0.50-1.18)

 

Systolic BP (mmHg)

135.9 (17.1)

0.86 (0.69-1.12)

 

0.88 (0.61-1.25)

 

Diastolic BP (mmHg)

72.2 (10.9)

0.65* (0.46-0.95)

0.65*(0.46-0.95)

0.98 (0.59-1.78)

 

Insulin user (%)

33.90%

0.97 (0.51-1.64)

 

3.48*(1.42-15.24)

3.48*(1.42-15.24)

CVA = < 70 y.o.

Mean(SD)

Hgb A1C = < 7.0 (Gp.MF)

7.0 < HgbA1C (Gp.MP)

Number of events

 

17

15

  

Univariate

Multivariate

Univariate

Multivariate

Male/Female

1.16

1.16 (0.65-2.26)

 

1.06(0.58-1.98)

 

Age (y.o.)

60.9 (7.9)

1.01 (0.94-1.11)

 

1.02(0.94-1.13)

 

Duration of diabetes (years)

9.15 (8.22)

0.81*(0.60-0.99)

 

1.08*(1.01-1.14)

1.06*(1.01-1.11)

HemoglobinA1C(%)

7.38 (1.31)

4.34*(1.07-25.8)

4.11+(1.01-13.40)

0.77(0.35-1.35)

 

Triglyceride (mg/dl)

146.9(129.5)

1.00 (0.98-1.02)

 

1.01(0.97-1.07)

 

LDL-Chol (mg/dl)

119.2 (34.1)

0.99 (0.96-1.14)

 

0.98(0.79-1.17)

 

HDL-Chol (mg/dl)

55.4 (16.2)

0.78 (0.49-1.18)

 

0.60**(0.35-0.63)

0.43**(0.23-0.78)

Systolic BP (mmHg)

133.5 (17.5)

0.98 (0.71-1.41)

 

0.99(0.75-1.44)

 

Diastolic BP (mmHg)

75.5 (11.7)

1.26 (0.76-2.17)

 

1.01(0.62-1.83)

 

Insulin user (%)

32.80%

0.89 (0.35-1.77)

 

0.74(0.35-1.18)

 

CVA 70 < y.o.

Mean(SD)

Hgb A1C = < 7.0 (Gp.OF)

7.0 < HgbA1C (Gp.OP)

Number of events

 

16

22

  

Univariate

Multivariate

Univariate

Multivariate

Male/Female

0.96

1.33 (0.79-2.40)

 

0.68 (0.36-1.17)

 

Age (y.o.)

75.4 (4.3)

1.04 (0.93-1.14)

 

1.05 (0.93-1.17)

 

Duration of diabetes (years)

10.18 (9.08)

1.01 (0.96-1.05)

 

1.04 (0.98-1.09)

 

HemoglobinA1C(%)

7.26 (1.15)

1.27 (0.47-4.29)

 

0.74 (035-1.32)

 

Triglyceride (mg/dl)

129.2 (62.2)

1.01 (0.91-1.07)

 

1.05 (0.97-1.19)

 

LDL-Chol (mg/dl)

116.1 (30.6)

0.96 (0.74-1.10)

 

1.04 (0.88-1.21)

 

HDL-Chol (mg/dl)

54.7 (16.2)

0.61*(0.38-0.93)

 

0.71*(0.47-1.02)

0.71 + (0.49-1.02)

Systolic BP (mmHg)

135.9 (17.1)

0.80 (0.64-1.04)

 

1.25 (0.91-1.72)

 

Diastolic BP (mmHg)

72.2 (10.9)

0.83 (0.55-1.34)

 

1.09 (0.68-1,85)

 

Insulin user (%)

33.90%

1.93* (1.05-3.62)

1.93* (1.05-3.62)

1.11 (0.53-2.24)

 
  1. +P < 0.1, *P < 0.05, **P < 0.01
  2. Clinical characteristics of diabetic individuals and the results of the univariate and multiple regression analyses examining the association between various clinical variables and IHD and CVA risk with stratification by age group. Patients were divided into two age categories: ≤ 70 years of age vs. > 70 years of age. Odds ratios and the corresponding 95% confidence intervals, which are in parentheses following the odds ratios, are shown. Abbreviations: Male/Female: ratio of male patients to female patients; Hemoglobin A1C (%): glycated hemoglobin A1C; LDL-C (mg/dl): Low-density lipoprotein cholesterol; HDL-C (mg/dl): High-density lipoprotein cholesterol; Systolic BP (mmHg): systolic blood pressure; Diastolic BP (mmHg): diastolic blood pressure.
  3. Bold characters indicate that a factor was found to be statistically significant by the univariate or multivariate regression analyses (p < 0.05).
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Cardiovascular Diabetology

ISSN: 1475-2840