Effects of calcium channel blockers on glucose tolerance, inflammatory state, and circulating progenitor cells in non-diabetic patients with essential hypertension: a comparative study between Azelnidipine and amlodipine on Glucose tolerance and ENdothelial function - a crossover Trial (AGENT)

Table 3 Comparison of 75 g oral glucose tolerance test between treatment with azelnidipine and amlodipine

	Baseline	Azelnidipine N = 17	Amlodipine N = 17	P**
Glucose 0, mg/dL	96 ± 8	94 ± 7	94 ± 8	0.826
Glucose 30, mg/dL	174 ± 28	162 ± 34	172 ± 25	0.160
Glucose 60, mg/dL	172 ± 37	181 ± 48	171 ± 41	0.221
Glucose 120, mg/dL	137 ± 30	130 ± 36	149 ± 30	0.039
IRI 0, μIU/mL	6.9 ± 4.2	7.0 ± 3.0	7.0 ± 3.5	0.957
IRI 30, μIU/mL	39.7 ± 16.9	39.8 ± 21.1	42.4 ± 20.8	0.660
IRI 60, μIU/mL	55.9 ± 29.8	56.1 ± 26.4	51.8 ± 27.3	0.465
IRI 120, μIU/mL	44.0 ± 26.8	47.7 ± 36.4	57.2 ± 37.9	0.026

Data are mean ± SD. IRI; immunoreactive insulin. ** azelnidipine vs. amlodipine.

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