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Table 2 Comparison of risk factors of cardiovascular disease and different cardiovascular disease manifestations

From: Plasma osteoprotegerin is related to carotid and peripheral arterial disease, but not to myocardial ischemia in type 2 diabetes mellitus

 

Carotid arterial disease

No carotid arterial disease

 

Co-variables

(n = 129)

(n = 176)

p

Blood pressure, systolic (mmHg)

137 ± 19

141 ± 17

0.028

Blood pressure, diastolic (mmHg)

80 ± 11

79 ± 11

0.649

HbA1c (%)

7.3 ± 1.2

7.3 ± 1.3

0.851

U-albumin creatinine ratio (mg/mmol)*

0.6 (0.0-2.8)

1.0 (0.0-4.3)

0.467

Total cholesterol (mmol/l)

4.4 ± 1.2

4.4 ± 0.9

0.861

LDL cholesterol (mmol/l)

2.2 ± 0.9

2.2 ± 0.8

0.930

HDL cholesterol (mmol/l)

1.31 ± 0.36

1.26 ± 0.33

0.193

Triglycerides (mmol/l)

1.97 ± 0.11

2.15 ± 0.10

0.236

Hs-CRP (mg/l)*

2.6 (1.3-6.3)

3.0 (1.7-7.5)

0.306

Osteoprotegerin (μg/l)*

1.28 (0.99-1.61)

1.04 (0.80-1.33)

< 0.001

 

Peripheral arterial disease

No peripheral arterial disease

 

Co-variables

(n = 45)

(n = 260)

P

Blood pressure, systolic (mmHg)

138 ± 18

143 ± 19

0.064

Blood pressure, diastolic (mmHg)

80 ± 11

76 ± 11

0.033

HbA1c (%)

7.3 ± 1.3

7.6 ± 1.2

0.084

U-albumin creatinine ratio (mg/mmol)*

0.6 (0.0-19.9)

0.8 (0.0-3.0)

0.098

Total cholesterol (mmol/l)

4.4 ± 1.2

4.4 ± 1.0

0.930

LDL cholesterol (mmol/l)

2.1 ± 0.9

2.2 ± 0.8

0.930

HDL cholesterol (mmol/l)

1.34 ± 0.41

1.27 ± 0.33

0.195

Triglycerides (mmol/l)

2.09 ± 1.47

2.07 ± 1.26

0.926

Hs-CRP (mg/l)*

3.5 (1.4-7.5)

2.8 (1.4-6.9)

0.607

Osteoprotegerin (μg/l)*

1.47 (1.02-1.89)

1.08 (0.85-1.40)

< 0.001

 

Myocardial ischemia

No myocardial ischemia

 

Co-variables

(n = 92)

(n = 213)

p

Blood pressure, systolic (mmHg)

141 ± 18

138 ± 18

0.117

Blood pressure, diastolic (mmHg)

81 ± 9

79 ± 11

0.164

HbA1c (%)

7.5 ± 1.4

7.2 ± 1.2

0.064

U-albumin creatinine ratio (mg/mmol)*

1.1 (0.0-4.0)

0.6 (0.0-3.3)

0.435

Total cholesterol (mmol/l)

4.3 ± 1.0

4.4 ± 1.0

0.750

LDL cholesterol (mmol/l)

2.2 ± 0.8

2.2 ± 0.8

0.931

HDL cholesterol (mmol/l)

1.23 ± 0.32

1.30 ± 0.35

0.118

Triglycerides (mmol/l)

2.09 ± 1.14

2.07 ± 1.36

0.924

Hs-CRP (mg/l)*

4.1 (1.3-7.4)

2.8 (1.5-6.4)

0.419

Osteoprotegerin (μg/l)*

1.11 (0.87-1.55)

1.11 (0.89-1.43)

0.711

  1. Data are means ± SD or median (interquartile range). * tested with the Mann-Whitney nonparametric test.
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Cardiovascular Diabetology

ISSN: 1475-2840