Skip to main content

Table 1 Characteristics of the type 2 diabetes patients

From: Plasma osteoprotegerin is related to carotid and peripheral arterial disease, but not to myocardial ischemia in type 2 diabetes mellitus

 

Total

CVD by examination

No CVD by examination

 

(n = 305)

(n = 183)

(n = 122)

Females/males

139/166

77/106

62/60

Age (years)

58.6 ± 11.3

60.7 ± 11.1 ††

55.3 ± 11.0

Diabetes duration (years)

4.5 ± 5.3

4.7 ± 5.5

4.1 ± 4.9

BMI (kg/m2)

32.2 ± 5.8

32.3 ± 6.3

32.2 ± 5.0

Waist circumference (cm)

107.9 ± 14.3

108.2 ± 15.0

107.5 ± 13.1

Hip circumference (cm)

110.2 ± 11.5

110.3 ± 12.3

110.2 ± 10.2

Blood pressure, systolic (mmHg)

138.7 ± 18.1

140.1 ± 17.0

136.6 ± 19.6

Blood pressure, diastolic (mmHg)

79.5 ± 10.9

79.3 ± 10.4

79.8 ± 11.7

Antidiabetic medical treatment

   

No antidiabetic treatment

65 (21)

40 (22)

25 (20)

Metformine

189 (62)

107 (58)

82 (67)

Rosiglitazone

19 (6)

14 (8)

5 (4)

DPP-IV-inhibitor

5 (2)

4 (2)

1 (1)

Sulphonylurea

76 (25)

46 (25)

30 (25)

Insulin

73 (24)

46 (25)

27 (22)

Blood samples/urine samples

   

Fasting p-glucose (mmol/l)

8.6 ± 2.5

8.8 ± 2.5

8.4 ± 2.4

HbA1c (%)

7.3 ± 1.3

7.5 ± 1.3 †

7.1 ± 1.2

Fasting C-peptide (pmol/l)

1146 ± 644

1169 ± 688

1112 ± 573

Fasting insulin (pmol/l)

106 ± 104

112 ± 119

96 ± 77

Total cholesterol conc. (mmol/l)

4.4 ± 1.0

4.4 ± 1.1

4.3 ± 0.9

LDL-cholesterol conc. (mmol/l)

2.2 ± 0.8

2.2 ± 0.9

2.1 ± 0.7

HDL-cholesterol conc. (mmol/l)

1.28 ± 0.34

1.29 ± 0.34

1.26 ± 0.35

Triglycerides (mmol/l)

2.07 ± 1.29

2.06 ± 1.31

2.09 ± 1.27

Creatinine (μmol/l)

90 ± 24

91 ± 24

88 ± 25

U-albumin creatinine ratio (mg/mmol)*

0.8 (0.0-3.5)

0.8 (0.0-3.1)

0.8 (0.0-3.8)

Hs-CRP (mg/l)*

2.9 (1.4-6.9)

3.0 (1.3-6.8)

2.8 (1.6-7.2)

Osteoprotegerin (μg/l)*

1.11 (0.88-1.46)

1.22 (0.94-1.54) ††

1.05 (0.78-1.24)

Risk factors for CVD

   

Family history of CVD#

58 (19)

31 (17)

26 (21)

Hypertension##

197 (64)

124 (68)

72 (59)

Hypercholesterolemia##

193 (63)

113 (62)

80 (66)

Current smoker

82 (27)

49 (27)

32 (26)

Angina pectoris

   

None

236 (77)

139 (76)

97 (80)

Non-cardiac chest pain

40 (13)

24 (13)

16 (13)

Atypical angina pectoris

17 (6)

11 (6)

6 (5)

Typical angina pectoris

12 (4)

9 (5)

3 (2)

  1. Data are means ± SD, (*median (interquartile range)) or n (%). CVD by examination = cardiovascular disease obtained from B-mode ultrasound scans of the carotid arteries, ankle and toe systolic blood pressure measurements and/or myocardial perfusion scintigraphy.
  2. Patients with CVD vs. without CVD by examination: † = p < 0.05. †† = p < 0.01.
  3. DDP-IV-inhibitor = Dipeptidyl peptidase IV inhibitor treatment. See text for definitions.
  4. # A positive family history of cardiovascular disease defined as cardiovascular disease either in male first-degree relative < 55 years or in female first-degree relative < 65 years.
  5. ## A medical history of hypertension or hypercholesterolemia, respectively.
  6. * tested with the Mann-Whitney nonparametric test.
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840