Table 2 Summary of serum chemical data
Laboratory test | Olmesartan (n = 168) | Candesartan (n = 266) | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | Mean | 95% CI | p-value | Mean | 95% CI | p-value | ||
| Â | Â | Lower | Upper | Â | Â | Lower | Upper | Â |
Lipid metabolism | Â | Â | Â | Â | Â | Â | Â | |
   Triglyceride (mmol/L) |  |  |  |  |  |  |  | |
Baseline | 1.87 | 1.68 | 2.06 | Â | 1.69 | 1.48 | 1.91 | Â |
Exposure | 1.76 | 1.58 | 1.94 | 0.3912 | 1.81 | 1.65 | 1.97 | 0.3862 |
   LDL-cholesterol (mmol/L) |  |  |  |  |  |  |  | |
Baseline | 3.01 | 2.88 | 3.14 | Â | 3.14 | 3.05 | 3.24 | Â |
Exposure | 2.93 | 2.81 | 3.05 | 0.3609 | 3.09 | 2.99 | 3.19 | 0.4478 |
   Total cholesterol (mmol/L) |  |  |  |  |  |  | ||
Baseline | 5.25 | 5.10 | 5.40 | Â | 5.34 | 5.21 | 5.46 | Â |
Exposure | 5.14 | 4.99 | 5.28 | 0.2871 | 5.31 | 5.19 | 5.43 | 0.7509 |
Kidney function | Â | Â | Â | Â | Â | Â | Â | |
   Urea nitrogen (mmol/L) |  |  |  |  |  |  | ||
Baseline | 5.63 | 5.29 | 5.97 | Â | 5.75 | 5.49 | 6.00 | Â |
Exposure | 5.92 | 5.50 | 6.34 | 0.2969 | 6.03 | 5.71 | 6.34 | 0.1743 |
   Creatinine (μmol/L) |  |  |  |  |  |  |  | |
Baseline | 70.00 | 66.57 | 73.44 | Â | 75.58 | 72.04 | 79.13 | Â |
Exposure | 72.31 | 68.66 | 75.95 | 0.3645 | 78.20 | 74.11 | 82.30 | 0.3416 |
   Potassium (mmol/L) |  |  |  |  |  |  |  | |
Baseline | 4.40 | 4.34 | 4.47 | Â | 4.32 | 4.27 | 4.36 | Â |
Exposure | 4.47 | 4.41 | 4.54 | 0.1161 | 4.36 | 4.31 | 4.41 | 0.2339 |