Table 1 Comparison of biochemical parameters amongst C57, eNOS-/- and DDAH mice before (baseline) and after feeding a high fat diet (week 13).

Glucose [mmol/l]

8.34 ± 2.20

9.91 ± 1.31*

8.80 ± 1.07

9.89 ± 1.15

9.14 ± 1.94

9.28 ± 1.92*

Insulin [mU/l]

7.91 ± 5.04

10.07 ± 4.32

5.52 ± 2.40

11.51 ± 6.24**

6.24 ± 3.84

10.55 ± 5.52*

QUICKI ^a

0.52 ± 0.07

0.44 ± 0.02*

0.52 ± 0.07

0.46 ± 0.07**

0.54 ± 0.09

0.45 ± 0.05*

HOMA ^b

0.27 ± 0.17

0.51 ± 0.19**

0.25 ± 0.13

0.49 ± 0.31**

0.24 ± 0.16

0.51 ± 0.32**