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Table 1 Comparison of biochemical parameters amongst C57, eNOS-/- and DDAH mice before (baseline) and after feeding a high fat diet (week 13).

From: Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance

  C57 eNOS-/- DDAH
  baseline 13 week baseline 13 week baseline 13 week
Glucose [mmol/l] 8.34 ± 2.20 9.91 ± 1.31* 8.80 ± 1.07 9.89 ± 1.15 9.14 ± 1.94 9.28 ± 1.92*
Insulin [mU/l] 7.91 ± 5.04 10.07 ± 4.32 5.52 ± 2.40 11.51 ± 6.24** 6.24 ± 3.84 10.55 ± 5.52*
QUICKI a 0.52 ± 0.07 0.44 ± 0.02* 0.52 ± 0.07 0.46 ± 0.07** 0.54 ± 0.09 0.45 ± 0.05*
HOMA b 0.27 ± 0.17 0.51 ± 0.19** 0.25 ± 0.13 0.49 ± 0.31** 0.24 ± 0.16 0.51 ± 0.32**
  1. a QUICKI = 1/[log(I) + log(G), where I is fasting insulin (mU/l) and G is fasting glucose (mg/dl)
  2. b HOMA = G * I/22.5, where I is fasting insulin (mU/l) and G is fasting glucose (mmol/l)
  3. *p < 0.05; **p < 0.01: significance between baseline and after13 weeks of feeding (week 13)