Table 2 Characteristics of patients with a major increase in IMT z-scores of ≥ 1.5 SD over 4 years in comparison to the remaining patients
cIMT- z-score increase ≥1.5 SD (n = 11) | cIMT z-score increase < 1.5 SD (n = 55) | p-value of mean difference | |
|---|---|---|---|
Age_2 (at 2nd cIMT measurement) (years) | 17.59 ± 2.87 | 16.08 ± 2.48 | 0.078 |
Age at disease manifestation (years) | 6.97 ± 4.02 | 7.44 ± 3.77 | 0.71 |
Diabetes duration_2 | 10.85 ± 3.92 | 8.77 ± 2.93 | 0.047 |
Puberty_2 (early-mid pubertal/late or postpubertal) | 2/9 | 25/30 | 0.096 |
Microalbuminuria and ACEi treatment_2 (patients) | 4 | 11 | 0.42 |
Smoking_2 (patients) | 2 | 8 | 0.741 |
HbA1c_1 (1st measurement) (%) | 6.99 ± 0.51 | 7.27 ± 0.77 | 0.250 |
HbA1c_2 (%) | 7.60 ± 0.77 | 8.23 ± 1.08 | 0.085 |
LDL-cholesterol_2 (mg/dl) | 84.27 ± 23.11 | 86.73 ± 28.66 | 0.79 |
HDL-cholesterol_2 (mg/dl) | 65.27 ± 16.30 | 62.69 ± 15.52 | 0.62 |
Leptin (μg/L) | 11.51 ± 6.32 | 8.08 ± 8.03 | 0.219 |
Adiponectin (μg/L) | 12.69 ± 5.74 | 13.54 ± 4.13 | 0.619 |
Systolic blood pressure_1 (mmHg) | 116.50 ± 8.86 | 107.81 ± 10.31 | 0.011 |
Systolic blood pressure_1 z-score | 0.99 ± 0.95 | 0.49 ± 0.74 | 0.056 |
Systolic blood pressure_2 (mmHg) | 128.20 ± 12.30 | 121.41 ± 11.15 | 0.086 |
Systolic blood pressure_2 z-score | 1.77 ± 1.28 | 1.29 ± 1.03 | 0.192 |
BMI_1 z-score | 0.82 ± 0.95 | 0.33 ± 0.88 | 0.796 |
BMI_2 z-score | 0.91 ± 1.03 | 0.82 ± 1.10 | 0.103 |
cIMT-1 z-score | 2.13 ± 0.48 | 1.81 ± 0.62 | 0.578 |
cIMT-2 z-score | 3.83 ± 0.43 | 2.16 ± 0.84 | <0.001 |